Page last updated: 2024-11-13

sansalvamide a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

sansalvamide A: a cyclic depsipeptide; inhibits poxvirus topoisomerase; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID44426202
CHEMBL ID228860
MeSH IDM0305655

Synonyms (2)

Synonym
CHEMBL228860
sansalvamide a

Research Excerpts

Overview

Sansalvamide A is a cyclic depsipeptide produced by a marine fungus.

ExcerptReferenceRelevance
"Sansalvamide A is a cyclic depsipeptide produced by a marine fungus."( A novel peptide sansalvamide analogue inhibits pancreatic cancer cell growth through G0/G1 cell-cycle arrest.
Adrian, TE; Bell, RH; Ding, XZ; Gu, W; Milam, B; Roginsky, AB; Salabat, MR; Silverman, RB; Talamonti, MS; Ujiki, MB, 2006
)
1.4
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID292673Cytotoxicity against BxPC3 cells at 5 uM by [3H]thymidine inhibition assay2007Bioorganic & medicinal chemistry letters, Sep-15, Volume: 17, Issue:18
Identification of Sansalvamide a analog potent against pancreatic cancer cell lines.
AID292672Cytotoxicity against PL45 cells at 5 uM by [3H]thymidine inhibition assay2007Bioorganic & medicinal chemistry letters, Sep-15, Volume: 17, Issue:18
Identification of Sansalvamide a analog potent against pancreatic cancer cell lines.
AID292674Cytotoxicity against WS1 cells2007Bioorganic & medicinal chemistry letters, Sep-15, Volume: 17, Issue:18
Identification of Sansalvamide a analog potent against pancreatic cancer cell lines.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (26)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (3.85)18.2507
2000's14 (53.85)29.6817
2010's11 (42.31)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.93

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.93 (24.57)
Research Supply Index3.30 (2.92)
Research Growth Index5.23 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.93)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other26 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]