quercetin 3-O-gentiobioside: an antioxidant with hypoglycemic and anticholesteremic activities; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
quercetin 3-beta-gentiobioside : A quercetin O-glycoside in which the hydroxy hydrogen at position 3 of quercetin has been replaced by a gentiobiosyl group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 5320834 |
| CHEMBL ID | 1097317 |
| CHEBI ID | 136778 |
| MeSH ID | M000601767 |
| Synonym |
|---|
| 7431-83-6 |
| CHEBI:136778 |
| quercetin 3-beta-gentiobioside |
| 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-1-benzopyran-3-yl 6-o-beta-d-glucopyranosyl-beta-d-glucopyranoside |
| 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-1-benzopyran-3-yl beta-d-glucopyranosyl-(1->6)-beta-d-glucopyranoside |
| 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-1-benzopyran-3-yl beta-d-glucosyl-(1->6)-beta-d-glucoside |
| beta-d-glucosyl-(1->6)-beta-d-glucoside |
| quercetin beta-d-glucopyranosyl-(1->6)-beta-d-glucopyranoside |
| CHEMBL1097317 |
| quercetin 3-gentiobioside |
| 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-[[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one |
| AKOS032946005 |
| HY-N4089 |
| CS-0032092 |
| MS-30825 |
| GLXC-14772 |
| quercetin 3-o-gentiobioside |
| DTXSID701310649 |
| quercetin 3-o-diglucoside |
| 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-((((2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)oxy)methyl)tetrahydro-2h-pyran-2-yl)oxy)-4h-chromen-4-one |
| 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4h-chromen-4-one |
| Role | Description |
|---|---|
| Brassica napus metabolite | Any plant metabolite that is produced by rapeseed (Brassica napus). |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| quercetin O-glycoside | Any glycosyloxyflavone that is an O-glycosylated derivative of quercetin. |
| disaccharide derivative | A carbohydrate derivative that is formally obtained from a disaccharide. |
| tetrahydroxyflavone | Any hydroxyflavone carrying four hydroxy substituents. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID481892 | Inhibition of Hh/GLI1-mediated PTCH protein expression in human PANC1 cells after 24 hrs by Western blot | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Terpenoids and a flavonoid glycoside from Acacia pennata leaves as hedgehog/GLI-mediated transcriptional inhibitors. |
| AID481888 | Cytotoxicity against human DU145 cells after 24 hrs by fluorimetric microculture cytotoxicity assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Terpenoids and a flavonoid glycoside from Acacia pennata leaves as hedgehog/GLI-mediated transcriptional inhibitors. |
| AID481889 | Cytotoxicity against mouse C3H10T1/2 cells after 24 hrs by fluorimetric microculture cytotoxicity assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Terpenoids and a flavonoid glycoside from Acacia pennata leaves as hedgehog/GLI-mediated transcriptional inhibitors. |
| AID1782344 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as bacterial growth inhibition at 32 ug/ml measured after 18 hrs by resazurine dye based assay | 2021 | Journal of natural products, 11-26, Volume: 84, Issue:11 | Phytochemical Profiling and Biological Testing of the Constituents of the Australian Plant |
| AID481893 | Inhibition of Hh/GLI1-mediated Bcl2 protein expression in human PANC1 cells after 24 hrs by Western blot | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Terpenoids and a flavonoid glycoside from Acacia pennata leaves as hedgehog/GLI-mediated transcriptional inhibitors. |
| AID481891 | Inhibition of Hh/GLI1-mediated Bcl2 protein expression in human HaCaT cells expressing T-Rex system after 24 hrs by Western blot | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Terpenoids and a flavonoid glycoside from Acacia pennata leaves as hedgehog/GLI-mediated transcriptional inhibitors. |
| AID481887 | Cytotoxicity against human PANC1 cells after 24 hrs by fluorimetric microculture cytotoxicity assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Terpenoids and a flavonoid glycoside from Acacia pennata leaves as hedgehog/GLI-mediated transcriptional inhibitors. |
| AID1782345 | Antifungal activity against Cryptococcus neoformans var. grubii H99 ATCC 208821 assessed as fungal growth inhibition at 32 ug/ml measured after 3 days by resazurine dye based assay | 2021 | Journal of natural products, 11-26, Volume: 84, Issue:11 | Phytochemical Profiling and Biological Testing of the Constituents of the Australian Plant |
| AID481886 | Inhibition of Hh/GLI1-mediated transcription in human HaCaT cells expressing T-Rex system by luciferase reporter gene assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Terpenoids and a flavonoid glycoside from Acacia pennata leaves as hedgehog/GLI-mediated transcriptional inhibitors. |
| AID481890 | Inhibition of Hh/GLI1-mediated PTCH protein expression in human HaCaT cells expressing T-Rex system after 24 hrs by Western blot | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Terpenoids and a flavonoid glycoside from Acacia pennata leaves as hedgehog/GLI-mediated transcriptional inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (13.09) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||