Compounds > pulvomycin

Page last updated: 2024-12-10

pulvomycin

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Description

pulvomycin: isolated from culture MA-2465; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	11840976
MeSH ID	M0059602

Synonyms (9)

Synonym
PUL ,
(1s,2s,3e,5e,7e,10s,11s,12s)-12-[(2r,4e,6e,8z,10r,12e,14e,16z,18s,19z)-10,18-dihydroxy-12,16,19-trimethyl-11,22-dioxooxacyclodocosa-4,6,8,12,14,16,19-heptaen-2-yl]-2,11-dihydroxy-1,10-dimethyl-9-oxotrideca-3,5,7-trien-1-yl 6-deoxy-2,4-di-o-methyl-beta-l-g
pulvomycin
(4e,6r,7e,9e,11e,14s,15e,17e,19e,22s)-22-[(2s,3s,4s,6e,8e,10e,12s,13s)-3,12-dihydroxy-13-[(2r,3r,4s,5r,6r)-4-hydroxy-3,5-dimethoxy-6-methyloxan-2-yl]oxy-4-methyl-5-oxotetradeca-6,8,10-trien-2-yl]-6,14-dihydroxy-5,8,12-trimethyl-1-oxacyclodocosa-4,7,9,11,1
(1s,2s,3e,5e,7e,10s,11s,12s)-12-[(2s,4e,6e,8e,10s,12e,14e,16e,18r,19e)-10,18-dihydroxy-12,16,19-trimethyl-11,22-dioxooxacyclodocosa-4,6,8,12,14,16,19-heptaen-2-yl]-2,11-dihydroxy-1,10-dimethyl-9-oxotrideca-3,5,7-trien-1-yl 6-deoxy-2,4-di-o-methyl-beta-d-g
(1s,2s,3e,5e,7e,10s,11s,12s)-12-[(2r,4e,6e,8z,10r,12e,14e,16z,18s,19z)-10,18-dihydroxy-12,16,19-trimethyl-11,22-dioxoox
acyclodocosa-4,6,8,12,14,16,19-heptaen-2-yl]-2,11-dihydroxy-1,10-dimethyl-9-oxotrideca-3,5,7-trien-1-yl 6-deoxy-2,4-di-o-methyl-beta-l-galactopyranoside
Q27464588
(1s,2s,3e,5e,7e,10s,11s,12s)-12-[(2r,4e,6e,8z,10r,12e,14e,16z,18s,19z)-10,18-dihydroxy-12,16,19-trimethyl-11,22-dioxooxacyclodocosa-4,6,8,12,14,16,19-heptaen-2-yl]-2,11-dihydroxy-1,10-dimethyl-9-oxotrideca-3,5,7-trien-1-yl 6-deoxy-2,4-di-o-methyl-bet

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (33)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	13 (39.39)	18.7374
1990's	9 (27.27)	18.2507
2000's	5 (15.15)	29.6817
2010's	4 (12.12)	24.3611
2020's	2 (6.06)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	2 (6.06%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	31 (93.94%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
adenine [no description available]	2	1	0	6-aminopurines; purine nucleobase	Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
methanol Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.. primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.. methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.	1.94	1	0	alkyl alcohol; one-carbon compound; primary alcohol; volatile organic compound	amphiprotic solvent; Escherichia coli metabolite; fuel; human metabolite; mouse metabolite; Mycoplasma genitalium metabolite
spermine [no description available]	1.96	1	0	polyazaalkane; tetramine	antioxidant; fundamental metabolite; immunosuppressive agent
urea pseudourea: clinical use; structure. isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.	2.02	1	0	isourea; monocarboxylic acid amide; one-carbon compound	Daphnia magna metabolite; Escherichia coli metabolite; fertilizer; flour treatment agent; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
thiazoles [no description available]	5.32	10	0	1,3-thiazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
fucose Fucose: A six-member ring deoxysugar with the chemical formula C6H12O5. It lacks a hydroxyl group on the carbon at position 6 of the molecule.. L-fucopyranose : The pyranose form of L-fucose.. fucose : Any deoxygalactose that is deoxygenated at the 6-position.	2.1	1	0	fucopyranose; L-fucose	Escherichia coli metabolite; mouse metabolite
galactose aldohexose : A hexose with a (potential) aldehyde group at one end.	1.94	1	0
glycosides [no description available]	3.34	7	0
fusidic acid Fusidic Acid: An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed). It acts by inhibiting translocation during protein synthesis.. fusidic acid : A steroid antibiotic that is isolated from the fermentation broth of Fusidium coccineum.	1.96	1	0	11alpha-hydroxy steroid; 3alpha-hydroxy steroid; alpha,beta-unsaturated monocarboxylic acid; steroid acid; steroid antibiotic; sterol ester	EC 2.7.1.33 (pantothenate kinase) inhibitor; Escherichia coli metabolite; protein synthesis inhibitor
enacyloxin iia enacyloxin IIa: produced by Frateuria sp. W-315; structure given in first source	4.06	2	0
ge 2270 a GE 2270 A: from Planobispora rosea; inhibits bacterial protein synthesis in vitro by affecting specifically the GTP-bound form of elongation factor Tu; structure given in first source	5.32	10	0
guanosine diphosphate Guanosine Diphosphate: A guanine nucleotide containing two phosphate groups esterified to the sugar moiety.	3.38	7	0	guanosine 5'-phosphate; purine ribonucleoside 5'-diphosphate	Escherichia coli metabolite; mouse metabolite; uncoupling protein inhibitor
guanosine triphosphate Guanosine Triphosphate: Guanosine 5'-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety.	4.87	11	0	guanosine 5'-phosphate; purine ribonucleoside 5'-triphosphate	Escherichia coli metabolite; mouse metabolite; uncoupling protein inhibitor
efrotomycin efrotomycin: from Streptomyces lactamdurans; structure	7.38	2	0
futalosine futalosine: structure in first source	7.31	1	0	inosines
formycins Formycins: Pyrazolopyrimidine ribonucleosides isolated from Nocardia interforma. They are antineoplastic antibiotics with cytostatic properties.	1.94	1	0
mocimycin mocimycin: induces GTPase activity of EF-TU; N-demethyl analog of antibiotic X-5108; structure	5.73	16	0	C-glycosyl compound
aurodox Aurodox: Antibiotic obtained from a Streptomyces variant considered as possibly effective against Streptococcus pyogenes infections. It may promote growth in poultry.	1.97	1	0

Condition	Indicated	Relationship Strength	Studies	Trials
Actinomycetales Infections Infections with bacteria of the order ACTINOMYCETALES.	0	3.06	1	0
Carcinoma, Ehrlich Tumor A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.	0	1.94	1	0
Sarcoma, Epithelioid [description not available]	0	1.94	1	0
Reticulum Cell-Like Sarcoma, Yoshida [description not available]	0	1.94	1	0
Sarcoma A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.	0	1.94	1	0