Page last updated: 2024-11-05

isobutyl nitrate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID10974
CHEMBL ID401409
SCHEMBL ID324571
MeSH IDM0188593

Synonyms (21)

Synonym
nitric acid, 2-methylpropyl ester
nitric acid, isobutyl ester
isobutyl nitrate
CHEMBL401409
2-methylpropyl nitrate
356ef349vi ,
einecs 208-842-2
unii-356ef349vi
543-29-3
FT-0627374
AKOS015912697
SCHEMBL324571
isobutylnitrate
nitric acid 2-methylpropyl ester
isobutyl nitrate [mi]
2-methyl-1-propyl nitrate
DTXSID70202655
isobutylnitrat
methyl2-(pyrrolidin-3-yl)acetate
nitric acid isobutyl ester
Q27256428

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" To investigate short-term toxic effects and establish exposure parameters for chronic inhalation studies, F344/N rats and B6C3F1 mice were exposed to IBN vapors on a 6 hr/day + t90, 5 days/week schedule."( Prechronic inhalation toxicity studies of isobutyl nitrite.
Abdo, KM; Aranyi, C; Gaworski, CL; Hall, A; Jackson, CD; Levine, BS, 1992
)
0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID309710Vasodilatory effect in pig pulmonary artery assessed as inhibition of PGF2-alpha-induced contraction2007Bioorganic & medicinal chemistry letters, Nov-01, Volume: 17, Issue:21
NO donors. Part 16: investigations on structure-activity relationships of organic mononitrates reveal 2-nitrooxyethylammoniumnitrate as a high potent vasodilator.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's5 (62.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 39.10

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index39.10 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.56 (4.65)
Search Engine Demand Index53.49 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (39.10)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (12.50%)4.05%
Observational0 (0.00%)0.25%
Other7 (87.50%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]