arteannuin-b and Leukemia-P388

arteannuin-b has been researched along with Leukemia-P388* in 1 studies

Other Studies

1 other study(ies) available for arteannuin-b and Leukemia-P388

Article	Year
[Derivatives of arteannuin B with antileukemia activity]. Yao xue xue bao = Acta pharmaceutica Sinica, 1992, Volume: 27, Issue:4 Arteannuin B (I) was converted to hydroxy lactones (VII, VIII) by a mixture of formic acid and sulfuric acid. Compound VI and Compound VII both showed activity against leukemia P 388 cell in vitro. The rate of growth inhibition were 97.5% and 11.8% for (VI) and 80% and 52.6% for (VII) at the concentration of 10 and 1 micrograms/ml respectively. It seems that the antileukemia activity of 6-membered lactone is higher than that of 5-membered and the methylene group is necessary for the antileukemia activity. Topics: Animals; Antineoplastic Agents, Phytogenic; Artemisinins; Drugs, Chinese Herbal; Leukemia P388; Mice; Sesquiterpenes; Tumor Cells, Cultured	1992

Article

Year

[Derivatives of arteannuin B with antileukemia activity].

Yao xue xue bao = Acta pharmaceutica Sinica, 1992, Volume: 27, Issue:4

Arteannuin B (I) was converted to hydroxy lactones (VII, VIII) by a mixture of formic acid and sulfuric acid. Compound VI and Compound VII both showed activity against leukemia P 388 cell in vitro. The rate of growth inhibition were 97.5% and 11.8% for (VI) and 80% and 52.6% for (VII) at the concentration of 10 and 1 micrograms/ml respectively. It seems that the antileukemia activity of 6-membered lactone is higher than that of 5-membered and the methylene group is necessary for the antileukemia activity.

Topics: Animals; Antineoplastic Agents, Phytogenic; Artemisinins; Drugs, Chinese Herbal; Leukemia P388; Mice; Sesquiterpenes; Tumor Cells, Cultured

1992