Page last updated: 2024-11-12
arachidin-3
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
arachidin-3: an NSAID and antioxidant isolated from Arachis hypogaea; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Related Flora
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Arachis | genus | A plant genus of the family FABACEAE that includes peanuts.[MeSH] | Fabaceae | The large family of plants characterized by pods. Some are edible and some cause LATHYRISM or FAVISM and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various LECTINS like PHYTOHEMAGGLUTININS from PHASEOLUS. Many of them harbor NITROGEN FIXATION bacteria on their roots. Many but not all species of beans belong to this family.[MeSH] |
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 11380920 |
| CHEMBL ID | 2230264 |
| SCHEMBL ID | 20191281 |
| MeSH ID | M0551292 |
Synonyms (14)
| Synonym |
|---|
| 5-[(e)-2-(4-hydroxyphenyl)ethenyl]-2-[(e)-3-methylbut-1-enyl]benzene-1,3-diol |
| CHEMBL2230264 |
| arachidin-3 |
| SCHEMBL20191281 |
| ybp72rt3ke , |
| arachidin iii |
| trans-arachidin 3 |
| 87320-15-8 |
| arachidin-iii |
| arachidin 3 |
| 5-((e)-2-(4-hydroxyphenyl)vinyl)-2-((e)-3-methylbut-1-enyl)benzene-1,3-diol |
| 5-((1e)-2-(4-hydroxyphenyl)ethenyl)-2-((1e)-3-methyl-1-buten-1-yl)-1,3-benzenediol |
| 1,3-benzenediol, 5-((1e)-2-(4-hydroxyphenyl)ethenyl)-2-((1e)-3-methyl-1-buten-1-yl)- |
| arachidin iii- |
Research Excerpts
Bioavailability
| Excerpt | Reference | Relevance |
|---|---|---|
| "The therapeutic promise of trans-resveratrol (tRes) is limited by poor bioavailability following rapid metabolism." | ( Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors. Bratton, SM; Brents, LK; Doerksen, RJ; Liu, H; Medina-Bolivar, F; Nair, V; Nopo-Olazabal, L; Patel, RY; Prather, PL; Radominska-Pandya, A; Seely, KA, 2012) | 0.38 |
| "Prenylated stilbenoids may be preferable alternatives to tRes due to increased bioavailability via slowed metabolism." | ( Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors. Bratton, SM; Brents, LK; Doerksen, RJ; Liu, H; Medina-Bolivar, F; Nair, V; Nopo-Olazabal, L; Patel, RY; Prather, PL; Radominska-Pandya, A; Seely, KA, 2012) | 0.38 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (5)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1081914 | Antifungal activity against Phomopsis obscurans assessed as growth inhibition after 144 hr by NCCLS M27-A broth microdilution method | 2011 | Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5 | Biological activity of peanut (Arachis hypogaea) phytoalexins and selected natural and synthetic Stilbenoids. |
| AID1081912 | Antifungal activity against Botryotinia fuckeliana assessed as growth inhibition after 48 hr by NCCLS M27-A broth microdilution method | 2011 | Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5 | Biological activity of peanut (Arachis hypogaea) phytoalexins and selected natural and synthetic Stilbenoids. |
| AID1081913 | Antifungal activity against Phomopsis obscurans assessed as growth inhibition after 120 hr by NCCLS M27-A broth microdilution method | 2011 | Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5 | Biological activity of peanut (Arachis hypogaea) phytoalexins and selected natural and synthetic Stilbenoids. |
| AID1081911 | Antifungal activity against Botryotinia fuckeliana assessed as growth inhibition after 72 hr by NCCLS M27-A broth microdilution method | 2011 | Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5 | Biological activity of peanut (Arachis hypogaea) phytoalexins and selected natural and synthetic Stilbenoids. |
| AID1081919 | Octanol-water partition coefficient, log P of the compound by HPLC analysis | 2011 | Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5 | Biological activity of peanut (Arachis hypogaea) phytoalexins and selected natural and synthetic Stilbenoids. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (9)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.56
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.56) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||