Page last updated: 2024-11-12

arachidin-3

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

arachidin-3: an NSAID and antioxidant isolated from Arachis hypogaea; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
ArachisgenusA plant genus of the family FABACEAE that includes peanuts.[MeSH]FabaceaeThe large family of plants characterized by pods. Some are edible and some cause LATHYRISM or FAVISM and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various LECTINS like PHYTOHEMAGGLUTININS from PHASEOLUS. Many of them harbor NITROGEN FIXATION bacteria on their roots. Many but not all species of beans belong to this family.[MeSH]

Cross-References

ID SourceID
PubMed CID11380920
CHEMBL ID2230264
SCHEMBL ID20191281
MeSH IDM0551292

Synonyms (14)

Synonym
5-[(e)-2-(4-hydroxyphenyl)ethenyl]-2-[(e)-3-methylbut-1-enyl]benzene-1,3-diol
CHEMBL2230264
arachidin-3
SCHEMBL20191281
ybp72rt3ke ,
arachidin iii
trans-arachidin 3
87320-15-8
arachidin-iii
arachidin 3
5-((e)-2-(4-hydroxyphenyl)vinyl)-2-((e)-3-methylbut-1-enyl)benzene-1,3-diol
5-((1e)-2-(4-hydroxyphenyl)ethenyl)-2-((1e)-3-methyl-1-buten-1-yl)-1,3-benzenediol
1,3-benzenediol, 5-((1e)-2-(4-hydroxyphenyl)ethenyl)-2-((1e)-3-methyl-1-buten-1-yl)-
arachidin iii-

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
"The therapeutic promise of trans-resveratrol (tRes) is limited by poor bioavailability following rapid metabolism."( Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors.
Bratton, SM; Brents, LK; Doerksen, RJ; Liu, H; Medina-Bolivar, F; Nair, V; Nopo-Olazabal, L; Patel, RY; Prather, PL; Radominska-Pandya, A; Seely, KA, 2012
)
0.38
"Prenylated stilbenoids may be preferable alternatives to tRes due to increased bioavailability via slowed metabolism."( Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors.
Bratton, SM; Brents, LK; Doerksen, RJ; Liu, H; Medina-Bolivar, F; Nair, V; Nopo-Olazabal, L; Patel, RY; Prather, PL; Radominska-Pandya, A; Seely, KA, 2012
)
0.38
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID1081914Antifungal activity against Phomopsis obscurans assessed as growth inhibition after 144 hr by NCCLS M27-A broth microdilution method2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Biological activity of peanut (Arachis hypogaea) phytoalexins and selected natural and synthetic Stilbenoids.
AID1081912Antifungal activity against Botryotinia fuckeliana assessed as growth inhibition after 48 hr by NCCLS M27-A broth microdilution method2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Biological activity of peanut (Arachis hypogaea) phytoalexins and selected natural and synthetic Stilbenoids.
AID1081913Antifungal activity against Phomopsis obscurans assessed as growth inhibition after 120 hr by NCCLS M27-A broth microdilution method2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Biological activity of peanut (Arachis hypogaea) phytoalexins and selected natural and synthetic Stilbenoids.
AID1081911Antifungal activity against Botryotinia fuckeliana assessed as growth inhibition after 72 hr by NCCLS M27-A broth microdilution method2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Biological activity of peanut (Arachis hypogaea) phytoalexins and selected natural and synthetic Stilbenoids.
AID1081919Octanol-water partition coefficient, log P of the compound by HPLC analysis2011Journal of agricultural and food chemistry, Mar-09, Volume: 59, Issue:5
Biological activity of peanut (Arachis hypogaea) phytoalexins and selected natural and synthetic Stilbenoids.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's7 (77.78)24.3611
2020's1 (11.11)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.56

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.56 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.96 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.56)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]