| Assay ID | Title | Year | Journal | Article |
|---|
| AID254534 | Inhibitory constant against Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cells; nd = not determined | 2005 | Journal of medicinal chemistry, Sep-22, Volume: 48, Issue:19
| Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target. |
| AID254503 | Inhibitory constant against human deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cells; nd = not determined | 2005 | Journal of medicinal chemistry, Sep-22, Volume: 48, Issue:19
| Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target. |
| AID255966 | In vitro cytotoxicity aganist rat skeletal myoblasts (L-6 cells) after 72 hours | 2005 | Journal of medicinal chemistry, Sep-22, Volume: 48, Issue:19
| Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target. |
| AID81438 | Dose required to inhibit cytopathic effect of human immunodeficiency virus replication in MT-4 cells. | 1988 | Journal of medicinal chemistry, Oct, Volume: 31, Issue:10
| Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides. |
| AID255964 | In vitro inhibitory activity against Plasmodium falciparum as [3H]hypoxanthine (50 uL) incorporation at 37C | 2005 | Journal of medicinal chemistry, Sep-22, Volume: 48, Issue:19
| Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target. |
| AID255969 | Inhibitory constant against Trypanosoma brucei rhodesiense upon incubation with the compound at 37 degrees C under a 5% CO2 atmosphere for 72 hours | 2005 | Journal of medicinal chemistry, Sep-22, Volume: 48, Issue:19
| Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target. |
| AID105582 | Inhibitory activity against HIV-1 replication in MT-4 cells | 1989 | Journal of medicinal chemistry, Aug, Volume: 32, Issue:8
| 3'-Fluoro-2',3'-dideoxy-5-chlorouridine: most selective anti-HIV-1 agent among a series of new 2'- and 3'-fluorinated 2',3'-dideoxynucleoside analogues. |
| AID255970 | In vitro growth inhibitory activity against Leishmania donovani amastigotes at 37 degrees C under a 5% CO2 atmosphere for 96 hours | 2005 | Journal of medicinal chemistry, Sep-22, Volume: 48, Issue:19
| Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target. |
| AID255973 | In vitro growth inhibitory activity against Trypanosoma cruzi in rat L-6 cells upon incubation at 37 degrees C in 5% CO2 atmosphere for 4 days | 2005 | Journal of medicinal chemistry, Sep-22, Volume: 48, Issue:19
| Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target. |
| AID235486 | Selectivity index is the ratio of ED50 and CD50 values against inhibition of HIV-1 in MT-4 cells | 1989 | Journal of medicinal chemistry, Aug, Volume: 32, Issue:8
| 3'-Fluoro-2',3'-dideoxy-5-chlorouridine: most selective anti-HIV-1 agent among a series of new 2'- and 3'-fluorinated 2',3'-dideoxynucleoside analogues. |
| AID81069 | Cytotoxic dose required to reduce the viability of normal uninfected MT-4 cells. | 1988 | Journal of medicinal chemistry, Oct, Volume: 31, Issue:10
| Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides. |
| AID254450 | Inhibitory constant against Leishmania major deoxyuridine 5'-triphosphate nucleotidohydrolase; nd = not determined | 2005 | Journal of medicinal chemistry, Sep-22, Volume: 48, Issue:19
| Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target. |
| AID235875 | Ratio of CD50 to ED50 rvaluated for inhibition of HIV replication in MT-4 cells | 1988 | Journal of medicinal chemistry, Oct, Volume: 31, Issue:10
| Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides. |
| AID105376 | Cytotoxic dose in MT-4 cells | 1989 | Journal of medicinal chemistry, Aug, Volume: 32, Issue:8
| 3'-Fluoro-2',3'-dideoxy-5-chlorouridine: most selective anti-HIV-1 agent among a series of new 2'- and 3'-fluorinated 2',3'-dideoxynucleoside analogues. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |