Page last updated: 2024-11-06

rhodizonic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Rhodizonic acid is a bright red, water-soluble organic compound with the formula C6O6H2. It is a dibasic acid and the simplest member of the class of compounds known as cyclohexanediones. Rhodizonic acid is typically synthesized by the oxidation of hexahydroxybenzene with nitric acid. The molecule is a strong reducing agent and forms colored complexes with many metals. Rhodizonic acid was first isolated in 1837 by Woskresensky. The compound has garnered interest due to its potential applications in various fields, including analytical chemistry, where it is used as a reagent for the detection and determination of metals, and in materials science, where it is being explored for its potential use in the development of new batteries and solar cells. Rhodizonic acid is also of interest to researchers studying the chemistry of carbohydrates and other related compounds. Research on rhodizonic acid and its derivatives is ongoing and continues to provide valuable insights into the diverse properties of these compounds and their potential for technological applications. '

Cross-References

ID SourceID
PubMed CID67050
SCHEMBL ID916303
MeSH IDM0047390

Synonyms (18)

Synonym
inchi=1/c6h2o6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h7-8
5,6-dihydroxycyclohex-5-ene-1,2,3,4-tetrone
5-cyclohexene-1,2,3,4-tetrone, 5,6-dihydroxy-
5,6-dihydroxycyclohex-5-ene-1,2,3,4-tetraone
rhodizonic acid, disodium salt
118-76-3
nsc624150
rhodizonic acid
unii-ng86fbs267
einecs 204-276-5
ng86fbs267 ,
AKOS006228674
SCHEMBL916303
5,6-dihydroxy-5-cyclohexene-1,2,3,4-tetrone
DTXSID70151997
rhodizonsaure
dihydroxycyclohex-5-ene-1,2,3,4-tetrone
Q2823301

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" Complete prevention of those effects by catalase indicated that H2O2-induced damages should underlie both toxic processes."( Mechanism of tetrahydroxy-1,4-quinone cytotoxicity: involvement of CA2+ and H2O2 in the impairment of DNA replication and mitochondrial function.
de Souza-Pinto, NC; Hoffmann, ME; Vercesi, AE, 1996
)
0.29
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (31)

TimeframeStudies, This Drug (%)All Drugs %
pre-199010 (32.26)18.7374
1990's5 (16.13)18.2507
2000's5 (16.13)29.6817
2010's6 (19.35)24.3611
2020's5 (16.13)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 31.52

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index31.52 (24.57)
Research Supply Index3.53 (2.92)
Research Growth Index4.62 (4.65)
Search Engine Demand Index38.91 (26.88)
Search Engine Supply Index2.05 (0.95)

This Compound (31.52)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (3.03%)4.05%
Observational0 (0.00%)0.25%
Other32 (96.97%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]