Compounds > n-octyl-5-dithio-2-nitrobenzoic acid

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n-octyl-5-dithio-2-nitrobenzoic acid

Description

n-octyl-5-dithio-2-nitrobenzoic acid: used for determination & derivatization of protein thiols; interacts with SH-groups in the transmembrane domain of transport proteins; structure given in first source [MeSH]

Cross-References

ID Source	ID
PubMed CID	5235505
MeSH ID	M0214224

Synonyms (7)

Synonym
2-nitro-5-(octyldisulfanyl)benzoic acid
146019-29-6
dithio-octyl-nitrobenzoic acid
n-octyl-5-dithio-2-nitrobenzoic acid
benzoic acid, 2-nitro-5-(octyldithio)-
odnb
DTXSID30932749

Research

Studies (5)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	4 (80.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
2,2'-dipyridyl	1	bipyridine	chelator; ferroptosis inhibitor	2005	2005	19.0	low	0	0	0	1	0	0
bumetanide	1	amino acid; benzoic acids; sulfonamide	diuretic; EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor	1993	1993	31.0	low	0	0	1	0	0	0
methyl methanesulfonate	1	methanesulfonate ester	alkylating agent; apoptosis inducer; carcinogenic agent; genotoxin; mutagen	2005	2005	19.0	low	0	0	0	1	0	0
ethylmaleimide	1	maleimides	anticoronaviral agent; EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor; EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor; EC 2.7.1.1 (hexokinase) inhibitor	1993	1993	31.0	low	0	0	1	0	0	0
serine	1	L-alpha-amino acid; proteinogenic amino acid; serine family amino acid; serine zwitterion; serine	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	1995	1995	29.0	low	0	0	1	0	0	0
dithionitrobenzoic acid	5	nitrobenzoic acid; organic disulfide	indicator	1993	2005	27.8	high	0	0	4	1	0	0
4-chloromercuribenzenesulfonate	1	arenesulfonic acid; arylmercury compound		1993	1993	31.0	low	0	0	1	0	0	0
methyl methanethiosulfonate	1	sulfonic acid derivative; thiosulfonate ester	metabolite	2005	2005	19.0	low	0	0	0	1	0	0
dithiothreitol	1	1,4-dimercaptobutane-2,3-diol; butanediols; dithiol; glycol; thiol	chelator; human metabolite; reducing agent	1993	1993	31.0	low	0	0	1	0	0	0
2,2'-dipyridyl disulfide	1	organic disulfide; pyridines	oxidising agent	2005	2005	19.0	low	0	0	0	1	0	0
glutathione disulfide	1	glutathione derivative; organic disulfide	Escherichia coli metabolite; mouse metabolite	1995	1995	29.0	low	0	0	1	0	0	0
phalloidine	1	homodetic cyclic peptide		1995	1995	29.0	low	0	0	1	0	0	0
cysteine	2	cysteinium	fundamental metabolite	1995	2005	24.0	medium	0	0	1	1	0	0
guanosine diphosphate	1	guanosine 5'-phosphate; purine ribonucleoside 5'-diphosphate	Escherichia coli metabolite; mouse metabolite; uncoupling protein inhibitor	2005	2005	19.0	low	0	0	0	1	0	0
guanosine triphosphate	1	guanosine 5'-phosphate; purine ribonucleoside 5'-triphosphate	Escherichia coli metabolite; mouse metabolite; uncoupling protein inhibitor	2005	2005	19.0	low	0	0	0	1	0	0

Condition	Indicated	Studies	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020