| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
acetic acid
Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed). acetic acid : A simple monocarboxylic acid containing two carbons. | 1.96 | 1 | 0 | monocarboxylic acid | antimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent |
dimethyl sulfoxide
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.. dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents. | 1.98 | 1 | 0 | sulfoxide;
volatile organic compound | alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger |
dithionite
Dithionite: Dithionite. The dithionous acid ion and its salts. | 2.4 | 2 | 0 | sulfur oxide;
sulfur oxoanion | |
2,7-diaminomitosene
[no description available] | 2.38 | 2 | 0 | | |
mitomycin
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.. mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae. | 2.94 | 4 | 0 | mitomycin | alkylating agent;
antineoplastic agent |
porfiromycin
Porfiromycin: Toxic antibiotic of the mitomycin group, obtained from MITOMYCIN and also from Streptomyces ardus and other species. It is proposed as an antineoplastic agent, with some antibiotic properties. | 1.96 | 1 | 0 | | |
mitomycin a
mitomycin A: RN given refers to (1aS-(1aalpha,8beta,8aalpha,8balpha))-isomer; structure given in first source. mitomycin A : A member of the family of mitomycins that exhibits antibiotic and antitumour properties as well as a high level of toxicity. | 1.96 | 1 | 0 | ether;
mitomycin | alkylating agent;
antimicrobial agent;
antineoplastic agent;
toxin |
deuterium
Deuterium: The stable isotope of hydrogen. It has one neutron and one proton in the nucleus. | 7.39 | 2 | 0 | dihydrogen | |
phenyl acetate
phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid. | 1.96 | 1 | 0 | benzenes;
phenyl acetates | |
fr 900482
FR 900482: isolated from Streptomyces sandaensis; structure given in above source | 2.01 | 1 | 0 | | |
n-methylmitomycin a
[no description available] | 1.96 | 1 | 0 | | |
sodium borohydride
sodium borohydride: RN given refers to parent cpd | 1.98 | 1 | 0 | inorganic sodium salt;
metal tetrahydridoborate | |
10-decarbamoylmitomycin c
10-decarbamoylmitomycin C: RN given refers to the (1aS-(1aalpha,8beta,8aalpha,8balpha))-isomer; RN for cpd without isomeric designation not available 4/91 | 2.07 | 1 | 0 | | |
deoxyguanosine
[no description available] | 2 | 1 | 0 | purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
inosine
[no description available] | 2.04 | 1 | 0 | inosines;
purines D-ribonucleoside | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
allopurinol
Allopurinol: A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.. allopurinol : A bicyclic structure comprising a pyrazole ring fused to a hydroxy-substituted pyrimidine ring. | 1.98 | 1 | 0 | nucleobase analogue;
organic heterobicyclic compound | antimetabolite;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
gout suppressant;
radical scavenger |