| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
glycine
[no description available] | 2.01 | 1 | 0 | alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid | EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical |
mitomycin
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.. mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae. | 4.49 | 7 | 0 | mitomycin | alkylating agent;
antineoplastic agent |
palladium
Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46. | 2.44 | 2 | 0 | metal allergen;
nickel group element atom;
platinum group metal atom | |
fluorine
Fluorine: A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as fluoride (FLUORIDES) to prevent dental caries. | 2.03 | 1 | 0 | diatomic fluorine;
gas molecular entity | NMR chemical shift reference compound |
dimethyldioxirane
dimethyldioxirane: structure given in first source; powerful oxidizing agent | 2.01 | 1 | 0 | | |
fr 66979
FR 66979: structure given in first source; isolated from Streptomyces sandaensis | 2.72 | 3 | 0 | | |
3-amino-5-hydroxybenzoic acid
3-amino-5-hydroxybenzoic acid: direct precursor of 7-carbon amino starter-unit for biosyn of ansamycins. 3-amino-5-hydroxybenzoic acid : A monohydroxybenzoic acid that is 3-hydroxybenzoic acid carrying an additional amino substitutent at position 4. | 1.97 | 1 | 0 | aminobenzoic acid;
monohydroxybenzoic acid | |
fr 66973
FR 66973: antitumor antibiotic from Streptomyces sandaensis; more potent against B16 melanoma & P388 leukemia than mitomycin C; structure given in first source | 3.55 | 2 | 0 | | |
vinylglycine
vinylglycine: irreversible inhibitor of aspartate aminotransferase; structure. L-vinylglycine : A non-proteinogenic L-alpha-amino acid with a structure in which a vinyl group is bonded to the alpha-carbon of glycine. | 2.01 | 1 | 0 | glycine derivative;
L-alpha-amino acid zwitterion;
non-proteinogenic L-alpha-amino acid | EC 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitor |
glucosamine
D-glucosamine : An amino sugar whose structure comprises D-glucose having an amino substituent at position 2.. 2-amino-2-deoxy-D-glucopyranose : A D-glucosamine whose structure comprises D-glucopyranose having an amino substituent at position 2. | 1.97 | 1 | 0 | D-glucosamine | Escherichia coli metabolite;
geroprotector;
mouse metabolite |
mitosene
mitosene: structure given in first source | 2.01 | 1 | 0 | | |
alvocidib
alvocidib: structure given in first source. alvocidib : A synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is substituted by a 3-hydroxy-1-methylpiperidin-4-yl group at position 8 and by a chlorine at the 2' position (the (-)-3S,4R stereoisomer). A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation. | 3.19 | 1 | 0 | dihydroxyflavone;
hydroxypiperidine;
monochlorobenzenes;
tertiary amino compound | antineoplastic agent;
antirheumatic drug;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor |
piperidines
Piperidines: A family of hexahydropyridines. | 3.19 | 1 | 0 | | |
11-acetyl-8-carbamoyloxymethyl,4-formyl-6-methoxy-14-oxa-1,11-diazatetracyclo(7.4.1.0.0)tetradeca-2,4,6-trien-9-yl acetate
FK 317 dihydrobenzoxazine: a substituted dihyrobenzoxazine; structure given in first source | 2.01 | 1 | 0 | | |