| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
phenanthrene
phenanthrene : A polycyclic aromatic hydrocarbon composed of three fused benzene rings which takes its name from the two terms 'phenyl' and 'anthracene.' | 2.03 | 1 | 0 | ortho-fused polycyclic arene;
ortho-fused tricyclic hydrocarbon;
phenanthrenes | environmental contaminant;
mouse metabolite |
pyridoxal phosphate
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).. pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal. | 2.44 | 2 | 0 | methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6 phosphate | coenzyme;
cofactor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
1-anilino-8-naphthalenesulfonate
1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd. 8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8. | 2.01 | 1 | 0 | aminonaphthalene;
naphthalenesulfonic acid | fluorescent probe |
fluoranthene
fluoranthene: structure. fluoranthene : An ortho- and peri-fused polycyclic arene consisting of a naphthalene and benzene unit connected by a five-membered ring. | 2.03 | 1 | 0 | ortho- and peri-fused polycyclic arene | |
erythromycin
Erythromycin: A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.. erythromycin : Any of several wide-spectrum macrolide antibiotics obtained from actinomycete Saccharopolyspora erythraea (formerly known as Streptomyces erythraeus).. erythromycin A : An erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively. | 8.83 | 11 | 0 | cyclic ketone;
erythromycin | |
spectinomycin
Spectinomycin: An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of GONORRHEA.. spectinomycin dihydrochloride : A hydrochloride obtained by combining spectinomycin with two molar equivalents of hydrochloric acid. An antibiotic that is active against gram-negative bacteria and used (as its pentahydrate) to treat gonorrhea.. spectinomycin : A pyranobenzodioxin and antibiotic that is active against gram-negative bacteria and used (as its dihydrochloride pentahydrate) to treat gonorrhea. It is produced by the bacterium Streptomyces spectabilis. | 7.1 | 1 | 0 | cyclic acetal;
cyclic hemiketal;
cyclic ketone;
pyranobenzodioxin;
secondary alcohol;
secondary amino compound | antibacterial drug;
antimicrobial agent;
bacterial metabolite |
fucose
Fucose: A six-member ring deoxysugar with the chemical formula C6H12O5. It lacks a hydroxyl group on the carbon at position 6 of the molecule.. L-fucopyranose : The pyranose form of L-fucose.. fucose : Any deoxygalactose that is deoxygenated at the 6-position. | 2.17 | 1 | 0 | fucopyranose;
L-fucose | Escherichia coli metabolite;
mouse metabolite |
carbonates
Carbonates: Salts or ions of the theoretical carbonic acid, containing the radical CO2(3-). Carbonates are readily decomposed by acids. The carbonates of the alkali metals are water-soluble; all others are insoluble. (From Grant & Hackh's Chemical Dictionary, 5th ed). carbonates : Organooxygen compounds that are salts or esters of carbonic acid, H2CO3. | 2.25 | 1 | 0 | carbon oxoanion | |
tungsten
Tungsten: A metallic element with the atomic symbol W, atomic number 74, and atomic weight 183.85. It is used in many manufacturing applications, including increasing the hardness, toughness, and tensile strength of steel; manufacture of filaments for incandescent light bulbs; and in contact points for automotive and electrical apparatus. | 7.02 | 1 | 0 | chromium group element atom | micronutrient |
galactose
aldohexose : A hexose with a (potential) aldehyde group at one end. | 3.4 | 7 | 0 | | |
rhamnose
[no description available] | 2.08 | 1 | 0 | L-rhamnose | |
megalomicin a
megalomicin A: RN given refers to parent cpd; structure | 2.03 | 1 | 0 | amino oligosaccharide | |
triazoles
Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms. | 2.25 | 1 | 0 | 1,2,3-triazole | |
methylglucoside
[no description available] | 2.04 | 1 | 0 | | |
mycaminose
[no description available] | 7.72 | 3 | 0 | deoxyglucose derivative;
glucosamines | |
thymidine 5'-diphosphate
thymidine 5'-diphosphate: see also record for thymidine 3',5'-diphosphate, RN 2863-04-9. dTDP : A thymidine phosphate having a diphosphate group at the 5'-position. | 2.47 | 2 | 0 | pyrimidine 2'-deoxyribonucleoside 5'-diphosphate;
thymidine phosphate | Escherichia coli metabolite;
mouse metabolite |
mycarose
mycarose: RN given refers to (L-ribo)-isomer; structure given in first source; epi-axenose to lyxo configeration | 7.7 | 3 | 0 | dideoxyhexose derivative | |
2-deoxystreptamine
2-deoxystreptamine: RN given refers to parent cpd; structure.. 2-deoxystreptamine : An amino cyclitol consisting of scyllo-inositol with the hydroxy groups at positions 1 and 3 replaced by unsubstituted amino groups and that at position 2 replaced by hydrogen. | 3.17 | 1 | 0 | | |
glucosamine
D-glucosamine : An amino sugar whose structure comprises D-glucose having an amino substituent at position 2.. 2-amino-2-deoxy-D-glucopyranose : A D-glucosamine whose structure comprises D-glucopyranose having an amino substituent at position 2. | 2.72 | 3 | 0 | D-glucosamine | Escherichia coli metabolite;
geroprotector;
mouse metabolite |
erythronolide b
[no description available] | 2.02 | 1 | 0 | erythronolide | |
zithromax
Azithromycin: A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.. azithromycin : A macrolide antibiotic useful for the treatment of bacterial infections. | 2.11 | 1 | 0 | macrolide antibiotic | antibacterial drug;
environmental contaminant;
xenobiotic |
glycosides
[no description available] | 2.01 | 1 | 0 | | |
neomethymycin
neomethymycin: structure. neomethymycin : A twelve-membered macrolide antibiotic that is biosynthesised by Streptomyces venezuelae. | 2.42 | 2 | 0 | enone;
macrolide antibiotic;
monosaccharide derivative | bacterial metabolite |
methymycin
methymycin: structure. methymycin : A twelve-membered macrolide antibiotic that is biosynthesised by Streptomyces venezuelae. | 3.12 | 5 | 0 | enone;
macrolide antibiotic;
monosaccharide derivative | bacterial metabolite |
narbomycin
narbomycin: structure. narbomycin : A macrolide antibiotic that is narbonolide having a 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residue attached at position 6. It is biosynthesised by Streptomyces venezuelae. | 2.75 | 3 | 0 | enone;
macrolide antibiotic;
monosaccharide derivative | bacterial metabolite |
picromycin
picromycin: structure. pikromycin : A macrolide antibiotic that is biosynthesised by Streptomyces venezuelae. | 3.13 | 5 | 0 | enone;
macrolide antibiotic;
monosaccharide derivative | bacterial metabolite |
oleandrose
[no description available] | 2 | 1 | 0 | dideoxyhexose derivative | |
olivose
olivose: RN given for (D)-isomer | 2.44 | 2 | 0 | hexose | |
ru 66647
telithromycin: a ketolide; semisynthetic derivative of erythromycin with cycling of the C11-12 positions to form a carbamate ring to avoid acquired resistance to macrolides; binds 70S bacterial rRNA, specifically to the 23S part (23S RIBOSOMAL RNA), preventing protein synthesis; | 2.11 | 1 | 0 | | |
cladinose
cladinose: structure | 2.46 | 2 | 0 | | |
s-adenosylmethionine
(R)-S-adenosyl-L-methionine : An S-adenosyl-L-methionine that has R-configuration.. S-adenosyl-L-methionine zwitterion : A zwitterionic tautomer of S-adenosyl-L-methionine arising from shift of the proton from the carboxy group to the amino group.. (R)-S-adenosyl-L-methionine zwitterion : An S-adenosyl-L-methionine zwitterion that has R-configuration; major species at pH 7.3.. (S)-S-adenosyl-L-methionine zwitterion : An S-adenosyl-L-methionine zwitterion that has S-configuration; major species at pH 7.3.. S-adenosyl-L-methionine : A sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine. | 3.61 | 2 | 0 | organic cation;
sulfonium compound | coenzyme;
cofactor;
human metabolite;
micronutrient;
Mycoplasma genitalium metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite |
tylosin
[no description available] | 2.47 | 2 | 0 | | |
chalcomycin
chalcomycin: structure | 2.05 | 1 | 0 | | |
phenanthrenes
Phenanthrenes: POLYCYCLIC AROMATIC HYDROCARBONS composed of three fused BENZENE rings.. phenanthrenes : Any benzenoid aromatic compound that consists of a phenanthrene skeleton and its substituted derivatives thereof. | 2.03 | 1 | 0 | | |