chlorolissoclimide: structure given in first source; a labdane cytotoxin isolated from Lissoclinum voeltzkowi Michaelson [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 127675 |
| CHEMBL ID | 514096 |
| MeSH ID | M0213201 |
| Synonym |
|---|
| chlorolissoclimide |
| CHEMBL514096 |
| (3r)-3-[(1s)-2-[(1r,3s,4as,7s,8as)-7-chloro-3-hydroxy-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1h-naphthalen-1-yl]-1-hydroxyethyl]pyrrolidine-2,5-dione |
| 2,5-pyrrolidinedione, 3-(2-(7-chlorodecahydro-3-hydroxy-5,5,8a-trimethyl-2-methylene-1-naphthalenyl)-1-hydroxyethyl)- |
| 3-(2-(7-chlorodecahydro-3-hydroxy-5,5,8a-trimethyl-2-methylene-1-naphthalenyl)-1-hydroxyethyl)-2,5-pyrrolidinedione |
| 148717-91-3 |
| (3r)-3-{(1s)-2-[(1r,3s,4as,7s,8as)-7-chloro-3-hydroxy-5,5,8a-trimethyl-2-methylidenedecahydronaphthalen-1-yl]-1-hydroxyethyl}pyrrolidine-2,5-dione |
| 7AL , |
| 3-[2-(7-chloro-3-hydroxy-5,5,8a-trimethyl-2-methylidenedecahydronaphthalen-1-yl)-1-hydroxyethyl]-5-hydroxy-3,4-dihydro-2h-pyrrol-2-one |
| DTXSID80933468 |
| nsc787484 |
| nsc-787484 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID333125 | Cytotoxicity against human NCI60 cells | 2004 | Journal of natural products, Aug, Volume: 67, Issue:8 | Cytotoxic lissoclimide-type diterpenes from the molluscs Pleurobranchusalbiguttatus and Pleurobranchus forskalii. |
| AID333129 | Cytotoxicity against human H125 cells at 1.8 ug/mL by Valeriote soft agar disk diffusion method | 2004 | Journal of natural products, Aug, Volume: 67, Issue:8 | Cytotoxic lissoclimide-type diterpenes from the molluscs Pleurobranchusalbiguttatus and Pleurobranchus forskalii. |
| AID333127 | Cytotoxicity against human H116 cells at 1.5 ug/mL by Valeriote soft agar disk diffusion method | 2004 | Journal of natural products, Aug, Volume: 67, Issue:8 | Cytotoxic lissoclimide-type diterpenes from the molluscs Pleurobranchusalbiguttatus and Pleurobranchus forskalii. |
| AID333132 | Cytotoxicity against human CEM cells at 1.5 ug/mL by Valeriote soft agar disk diffusion method | 2004 | Journal of natural products, Aug, Volume: 67, Issue:8 | Cytotoxic lissoclimide-type diterpenes from the molluscs Pleurobranchusalbiguttatus and Pleurobranchus forskalii. |
| AID333126 | Cytotoxicity against human H116 cells at 1.8 ug/mL by Valeriote soft agar disk diffusion method | 2004 | Journal of natural products, Aug, Volume: 67, Issue:8 | Cytotoxic lissoclimide-type diterpenes from the molluscs Pleurobranchusalbiguttatus and Pleurobranchus forskalii. |
| AID333130 | Cytotoxicity against mouse L1210 cells at 1.5 ug/mL by Valeriote soft agar disk diffusion method | 2004 | Journal of natural products, Aug, Volume: 67, Issue:8 | Cytotoxic lissoclimide-type diterpenes from the molluscs Pleurobranchusalbiguttatus and Pleurobranchus forskalii. |
| AID1707193 | Antiproliferative activity against mouse P388 cells | 2020 | Journal of medicinal chemistry, 12-24, Volume: 63, Issue:24 | Development of Potential Antitumor Agents from the Scaffolds of Plant-Derived Terpenoid Lactones. |
| AID333133 | Cytotoxicity against human CEM cells at 1.8 ug/mL by Valeriote soft agar disk diffusion method | 2004 | Journal of natural products, Aug, Volume: 67, Issue:8 | Cytotoxic lissoclimide-type diterpenes from the molluscs Pleurobranchusalbiguttatus and Pleurobranchus forskalii. |
| AID333128 | Cytotoxicity against human H125 cells at 1.5 ug/mL by Valeriote soft agar disk diffusion method | 2004 | Journal of natural products, Aug, Volume: 67, Issue:8 | Cytotoxic lissoclimide-type diterpenes from the molluscs Pleurobranchusalbiguttatus and Pleurobranchus forskalii. |
| AID333134 | Cytotoxicity against human Colon 38 cells at 1.5 ug/mL by Valeriote soft agar disk diffusion method | 2004 | Journal of natural products, Aug, Volume: 67, Issue:8 | Cytotoxic lissoclimide-type diterpenes from the molluscs Pleurobranchusalbiguttatus and Pleurobranchus forskalii. |
| AID333135 | Cytotoxicity against human Colon 38 cells at 1.8 ug/mL by Valeriote soft agar disk diffusion method | 2004 | Journal of natural products, Aug, Volume: 67, Issue:8 | Cytotoxic lissoclimide-type diterpenes from the molluscs Pleurobranchusalbiguttatus and Pleurobranchus forskalii. |
| AID333131 | Cytotoxicity against mouse L1210 cells at 1.8 ug/mL by Valeriote soft agar disk diffusion method | 2004 | Journal of natural products, Aug, Volume: 67, Issue:8 | Cytotoxic lissoclimide-type diterpenes from the molluscs Pleurobranchusalbiguttatus and Pleurobranchus forskalii. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.88) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (12.50%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (87.50%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||