Target type: biologicalprocess
The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
The facial nerve, also known as the seventh cranial nerve, is a complex structure responsible for controlling facial expressions, taste sensation on the anterior two-thirds of the tongue, and transmitting sensory information from the ear. Its intricate organization is essential for its diverse functions. The development and organization of the facial nerve begin during embryogenesis. Neural crest cells migrate to form the facial nerve and its branches, which then undergo a series of coordinated events to establish its structure. The facial nerve is organized into four major components: the motor nucleus, the sensory nucleus, the parasympathetic nucleus, and the peripheral nerve fibers. The motor nucleus, located in the pons of the brainstem, controls the muscles of facial expression. The sensory nucleus, also located in the pons, receives sensory information from the ear. The parasympathetic nucleus, located in the pons, controls the salivary glands and tear glands. The peripheral nerve fibers, which extend from the brainstem to the face, transmit motor, sensory, and parasympathetic signals. The peripheral nerve fibers are organized into branches that innervate specific muscles and sensory structures. The facial nerve is a mixed nerve, meaning it carries both motor and sensory information. The motor fibers originate from the motor nucleus and innervate the muscles of facial expression, which are responsible for movements like smiling, frowning, and blinking. The sensory fibers originate from the sensory nucleus and innervate the ear, providing information about sound and balance. The parasympathetic fibers originate from the parasympathetic nucleus and innervate the salivary glands and tear glands, controlling the production of saliva and tears. The facial nerve is also involved in the development of the ear. The development of the ear is closely linked to the development of the facial nerve, as both structures originate from the same embryonic structures. During embryogenesis, the facial nerve and the ear develop together, with the facial nerve providing innervation to the muscles of the ear. The facial nerve's organization and function are critical for normal facial expression, taste perception, and ear sensory input. Any disruptions in the facial nerve's development or structure can lead to facial paralysis, taste disorders, and hearing impairments. Understanding the intricate organization of the facial nerve is essential for diagnosing and treating facial nerve disorders. This knowledge is also crucial for developing new therapeutic strategies for these disorders.'
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Protein | Definition | Taxonomy |
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Neuropilin-1 | A neuropilin-1 that is encoded in the genome of human. [PRO:WCB, UniProtKB:O14786] | Homo sapiens (human) |
Compound | Definition | Classes | Roles |
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ala-thr-trp-leu-pro-pro-arg | |||
EG00229 | benzothiadiazole; dicarboxylic acid monoamide; L-arginine derivative; secondary carboxamide; sulfonamide; thiophenes | angiogenesis inhibitor; antineoplastic agent; neuropilin receptor antagonist |