Page last updated: 2024-12-05

6-azaindole

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

6-Azaindole is a heterocyclic compound that is structurally similar to indole, with a nitrogen atom replacing the carbon atom at position 6. It is an important synthetic building block for various bioactive compounds, including pharmaceuticals and agrochemicals. 6-Azaindole has shown promising activity in different therapeutic areas, including anti-cancer, anti-inflammatory, and anti-microbial. Its synthesis is typically achieved through the condensation of o-aminobenzaldehyde with a suitable carbonyl compound. Research on 6-azaindole is driven by its potential applications in drug discovery and material science. Its unique chemical properties and biological activities make it a valuable target for further investigation.'

Cross-References

ID SourceID
PubMed CID9219
CHEMBL ID5208607
SCHEMBL ID12470
SCHEMBL ID22959960
MeSH IDM0490829

Synonyms (38)

Synonym
AC-1651
1,6-diazaindene
brn 0109685
harmyrine
1h-pyrrolo(2,3-c)pyridine
inchi=1/c7h6n2/c1-3-8-5-7-6(1)2-4-9-7/h1-5,9
6-azaindole ,
271-29-4
A-9495
1h-pyrrolo[2,3-c]pyridine
AKOS000782863
A5292
pyrrolo[2,3-c]pyridine
5-23-06-00305 (beilstein handbook reference)
271-28-3
AKOS006240281
6h-pyrrolo[2,3-c]pyridine
BP-20630
FT-0601477
PS-4926
6-azaindol
AM20051017
PB21773
SCHEMBL12470
mfcd01686899
SY005848
DTXSID20181562
1h-pyrrolo[2,3-c]pyridine, aldrichcpr
CS-W002819
BBL103029
STL556838
1h-inden-2-amine, 5,6-diethyl-2,3-dihydro-, hydrochloride (1:1)
BCP26482
EN300-56937
SCHEMBL22959960
P2530
Z871773918
CHEMBL5208607
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID1891831Lipid-water distribution ratio of the compound2022Journal of medicinal chemistry, 05-12, Volume: 65, Issue:9
Development of Azaindole-Based Frameworks as Potential Antiviral Agents and Their Future Perspectives.
AID1891830Basic dissociation constant, pKa of the compound2022Journal of medicinal chemistry, 05-12, Volume: 65, Issue:9
Development of Azaindole-Based Frameworks as Potential Antiviral Agents and Their Future Perspectives.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's4 (36.36)24.3611
2020's3 (27.27)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 22.78

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index22.78 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.68 (4.65)
Search Engine Demand Index21.17 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (22.78)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (9.09%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (90.91%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]