Pathways > G alpha (q) signalling events
Page last updated: 2024-10-06

G alpha (q) signalling events

Proteins (78)

ProteinSynonymsTaxonomy
Kininogen-1 Alpha-2-thiol proteinase inhibitor; Fitzgerald factor; High molecular weight kininogen; HMWK; Williams-Fitzgerald-Flaujeac factorHomo sapiens (human)
Oxytocin-neurophysin 1OT-NPIHomo sapiens (human)
PromotilinHomo sapiens (human)
Epidermal growth factor receptorEC 2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1Homo sapiens (human)
Protein kinase C alpha typePKC-A; PKC-alpha; EC 2.7.11.13Homo sapiens (human)
Thromboxane A2 receptor TXA2-R; Prostanoid TP receptorHomo sapiens (human)
Substance-P receptorSPR; NK-1 receptor; NK-1R; Tachykinin receptor 1Homo sapiens (human)
Mitogen-activated protein kinase 3 MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1Homo sapiens (human)
Mitogen-activated protein kinase 1MAP kinase 1; MAPK 1; EC 2.7.11.24; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2Homo sapiens (human)
Type-1 angiotensin II receptorAT1AR; AT1BR; Angiotensin II type-1 receptor; AT1Homo sapiens (human)
Gonadotropin-releasing hormone receptorGnRH receptor; GnRH-RHomo sapiens (human)
Histamine H1 receptorH1R; HH1RHomo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-kHomo sapiens (human)
Tyrosine-protein kinase BTKEC 2.7.10.2; Agammaglobulinemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinaseHomo sapiens (human)
Monoglyceride lipaseMGL; EC 3.1.1.23; HU-K5; Lysophospholipase homolog; Lysophospholipase-like; Monoacylglycerol lipase; MAGLHomo sapiens (human)
Cysteinyl leukotriene receptor 2CysLTR2; G-protein coupled receptor GPCR21; hGPCR21; G-protein coupled receptor HG57; HPN321Homo sapiens (human)
G-protein coupled receptor 143Ocular albinism type 1 proteinHomo sapiens (human)
G-protein coupled receptor family C group 6 member AhGPRC6A; G-protein coupled receptor GPCR33; hGPCR33Homo sapiens (human)
Free fatty acid receptor 1G-protein coupled receptor 40Homo sapiens (human)
Free fatty acid receptor 3G-protein coupled receptor 41Homo sapiens (human)
Stromelysin-1SL-1; EC 3.4.24.17; Matrix metalloproteinase-3; MMP-3; Transin-1Homo sapiens (human)
Substance-K receptorSKR; NK-2 receptor; NK-2R; Neurokinin A receptor; Tachykinin receptor 2Homo sapiens (human)
Neuromedin-K receptorNKR; NK-3 receptor; NK-3R; Neurokinin B receptor; Tachykinin receptor 3Homo sapiens (human)
Oxytocin receptorOT-RHomo sapiens (human)
Gastrin/cholecystokinin type B receptorCCK-B receptor; CCK-BR; Cholecystokinin-2 receptor; CCK2-RHomo sapiens (human)
Prostaglandin E2 receptor EP1 subtypePGE receptor EP1 subtype; PGE2 receptor EP1 subtype; Prostanoid EP1 receptorHomo sapiens (human)
Extracellular calcium-sensing receptorCaR; CaSR; hCasR; Parathyroid cell calcium-sensing receptor 1; PCaR1Homo sapiens (human)
P2Y purinoceptor 2P2Y2; ATP receptor; P2U purinoceptor 1; P2U1; P2U receptor 1; Purinergic receptorHomo sapiens (human)
Prostaglandin F2-alpha receptorPGF receptor; PGF2-alpha receptor; Prostanoid FP receptorHomo sapiens (human)
Glucagon receptorGL-RHomo sapiens (human)
P2Y purinoceptor 1P2Y1; ADP receptor; Purinergic receptorHomo sapiens (human)
Mitogen-activated protein kinase 7MAP kinase 7; MAPK 7; EC 2.7.11.24; Big MAP kinase 1; BMK-1; Extracellular signal-regulated kinase 5; ERK-5Homo sapiens (human)
Growth hormone secretagogue receptor type 1GHS-R; GH-releasing peptide receptor; GHRP; Ghrelin receptorHomo sapiens (human)
KiSS-1 receptorKiSS-1R; G-protein coupled receptor 54; G-protein coupled receptor OT7T175; hOT7T175; Hypogonadotropin-1; Kisspeptins receptor; Metastin receptorHomo sapiens (human)
Putative P2Y purinoceptor 10P2Y10; P2Y-like receptorHomo sapiens (human)
AngiotensinogenSerpin A8Homo sapiens (human)
Tachykinin-3ZNEUROK1Homo sapiens (human)
CholecystokininCCKHomo sapiens (human)
Cyclic AMP-responsive element-binding protein 1CREB-1; cAMP-responsive element-binding protein 1Homo sapiens (human)
Lysophosphatidic acid receptor 6LPA receptor 6; LPA-6; Oleoyl-L-alpha-lysophosphatidic acid receptor; P2Y purinoceptor 5; P2Y5; Purinergic receptor 5; RB intron encoded G-protein coupled receptorHomo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
Free fatty acid receptor 2G-protein coupled receptor 43Homo sapiens (human)
Motilin receptorG-protein coupled receptor 38Homo sapiens (human)
Orexin receptor type 1Ox-1-R; Ox1-R; Ox1R; Hypocretin receptor type 1Homo sapiens (human)
Orexin receptor type 2Ox-2-R; Ox2-R; Ox2R; Hypocretin receptor type 2Homo sapiens (human)
N-formyl peptide receptor 2FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFPHomo sapiens (human)
Beta-adrenergic receptor kinase 1Beta-ARK-1; EC 2.7.11.15; G-protein coupled receptor kinase 2Homo sapiens (human)
Platelet-activating factor receptorPAF-R; PAFrHomo sapiens (human)
G protein-coupled receptor kinase 5EC 2.7.11.16; G protein-coupled receptor kinase GRK5Homo sapiens (human)
Thyrotropin-releasing hormone receptorTRH-R; Thyroliberin receptorHomo sapiens (human)
P2Y purinoceptor 6P2Y6Homo sapiens (human)
Free fatty acid receptor 4G-protein coupled receptor 120; G-protein coupled receptor 129; G-protein coupled receptor GT01; G-protein coupled receptor PGR4; Omega-3 fatty acid receptor 1Homo sapiens (human)
Neuropeptide S receptorG-protein coupled receptor 154; G-protein coupled receptor PGR14; G-protein coupled receptor for asthma susceptibilityHomo sapiens (human)
P2Y purinoceptor 11P2Y11Homo sapiens (human)
Pyroglutamylated RF-amide peptide receptorAQ27; G-protein coupled receptor 103; Orexigenic neuropeptide QRFP receptor; SP9155Homo sapiens (human)
Lysophosphatidic acid receptor 4LPA receptor 4; LPA-4; G-protein coupled receptor 23; P2Y purinoceptor 9; P2Y9; P2Y5-like receptor; Purinergic receptor 9Homo sapiens (human)
Urotensin-2 receptorUR-2-R; G-protein coupled receptor 14; Urotensin II receptor; UR-II-RHomo sapiens (human)
Cysteinyl leukotriene receptor 1CysLTR1; Cysteinyl leukotriene D4 receptor; LTD4 receptor; G-protein coupled receptor HG55; HMTMF81Homo sapiens (human)
OrexinHypocretin; HcrtHomo sapiens (human)
G-protein coupled receptor 39Homo sapiens (human)
Uracil nucleotide/cysteinyl leukotriene receptorUDP/CysLT receptor; G-protein coupled receptor 17; P2Y-like receptor; R12Homo sapiens (human)
Proheparin-binding EGF-like growth factorHomo sapiens (human)
Neuropeptide SHomo sapiens (human)
Pro-glucagonHomo sapiens (human)
Neuromedin-U receptor 2NMU-R2; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1Homo sapiens (human)
Chemokine XC receptor 1G-protein coupled receptor 5; Lymphotactin receptor; XC chemokine receptor 1Homo sapiens (human)
MelanopsinOpsin-4Homo sapiens (human)
Metastasis-suppressor KiSS-1Kisspeptin-1Homo sapiens (human)
Pro-FMRFamide-related neuropeptide FFFMRFamide-related peptidesHomo sapiens (human)
Vasopressin-neurophysin 2-copeptinAVP-NPIIHomo sapiens (human)
GastrinHomo sapiens (human)
Protachykinin-1PPTHomo sapiens (human)
Pro-MCHHomo sapiens (human)
Neurotensin/neuromedin NHomo sapiens (human)
Neuromedin-UHomo sapiens (human)
Orexigenic neuropeptide QRFPP518Homo sapiens (human)
Neuromedin-SHomo sapiens (human)
Putative gonadotropin-releasing hormone II receptorGnRH II receptor; GnRH-II-R; Type II GnRH receptorHomo sapiens (human)

Compounds (23)

CompoundDescription
hydronium ion
AcetylcholineA neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
dinoprostoneThe most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.
dinoprostA naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
glycerolA trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. It is used as a solvent, emollient, pharmaceutical agent, or sweetening agent.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
guanosine diphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
SerotoninA biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
leukotriene b4The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)
leukotriene c4The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)
thromboxane a2An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).
glyceryl 2-arachidonatebinds to cannabinoid receptors; structure in first source
glutamate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Peremin
1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholinereported to have same biological activity as natural PAF-acether; RN given refers to parent cpd without isomeric designation
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