zedoarondiol: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 24834047 |
| CHEMBL ID | 2332880 |
| MeSH ID | M0542663 |
| Synonym |
|---|
| bdbm50429859 |
| CHEMBL2332880 , |
| 4,10-epizedoarondiol |
| zedoarondiol |
| 98644-24-7 |
| (3r,3as,8s,8ar)-3,8-dihydroxy-3,8-dimethyl-5-propan-2-ylidene-1,2,3a,4,7,8a-hexahydroazulen-6-one |
| 6(1h)-azulenone, octahydro-1,4-dihydroxy-1,4-dimethyl-7-(1-methylethylidene)-, (1r,3ar,4s,8as)- |
| (1r,3ar,4s,8as)-1,4-dihydroxy-1,4-dimethyl-7-(propan-2-ylidene)-decahydroazulen-6-one |
| DTXSID501317851 |
| HY-122915 |
| CS-0090428 |
| AKOS040760767 |
| (1r,3ar,4s,8as)-octahydro-1,4-dihydroxy-1,4-dimethyl-7-(1-methylethylidene)-6(1h)-azulenone |
| 6(1h)-azulenone, octahydro-1,4-dihydroxy-1,4-dimethyl-7-(1-methylethylidene)-, [1r-(1alpha,3aalpha,4beta,8abeta)]- |
| 2758Q22LPQ |
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Tyrosine-protein phosphatase non-receptor type 2 | Homo sapiens (human) | IC50 (µMol) | 15.7000 | 0.7000 | 4.5804 | 9.4500 | AID729839 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 (µMol) | 35.1000 | 0.0005 | 3.4984 | 9.7600 | AID729840 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID729839 | Inhibition of TCPTP (unknown origin) assessed as decrease in p-nitrophenol production from pNPP substrate after 30 mins by HTS7000 bioassay reader analysis | 2013 | Journal of natural products, Feb-22, Volume: 76, Issue:2 | Sesquiterpenes from the rhizomes of Curcuma heyneana. |
| AID729841 | Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenol production from pNPP substrate at 25 ug/ml after 30 mins by HTS7000 bioassay reader analysis | 2013 | Journal of natural products, Feb-22, Volume: 76, Issue:2 | Sesquiterpenes from the rhizomes of Curcuma heyneana. |
| AID729840 | Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenol production from pNPP substrate after 30 mins by HTS7000 bioassay reader analysis | 2013 | Journal of natural products, Feb-22, Volume: 76, Issue:2 | Sesquiterpenes from the rhizomes of Curcuma heyneana. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||