Page last updated: 2024-11-12
sarpagine
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
sarpagine: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
sarpagine : An indole alkaloid that is sarpagan bearing hydroxy groups at positions 10 and 17. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 12314884 |
| CHEBI ID | 9036 |
| MeSH ID | M0451975 |
Synonyms (20)
| Synonym |
|---|
| 10,17-sarpagandiol |
| CHEBI:9036 |
| raupin |
| sarpagan-10,17-diol |
| sarpagine |
| 482-68-8 |
| xd54mpv6vq , |
| einecs 207-583-2 |
| 6,10-methanoindolo(3,2-b)quinolizin-11-ylmethanol, 9-ethylidene-5,6,9,10,11,11a,12-octahydro-2-hydroxy- |
| unii-xd54mpv6vq |
| raupine [who-dd] |
| sarpagine [mi] |
| 6,10-methanoindolo(3,2-b)quinolizin-11-ylmethanol, 9- ethylidene-5,6,9,10,11,11a,12-octahydro-2-hydroxy- |
| (1s,12s,13r,14r,15e)-15-ethylidene-13-(hydroxymethyl)-3,17-diazapentacyclo[12.3.1.02,10.04,9.012,17]octadeca-2(10),4(9),5,7-tetraen-7-ol |
| (1s,12s,14r,15e)-15-ethylidene-13-(hydroxymethyl)-3,17-diazapentacyclo[12.3.1.02,10.04,9.012,17]octadeca-2(10),4(9),5,7-tetraen-7-ol |
| Q27108227 |
| DTXSID901023593 |
| HY-N1245 |
| CS-0016648 |
| AKOS040744640 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Drug Classes (5)
| Class | Description |
|---|---|
| indole alkaloid | An alkaloid containing an indole skeleton. |
| tertiary amino compound | A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups. |
| secondary amino compound | A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups. |
| phenols | Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring. |
| primary alcohol | A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Pathways (1)
| Pathway | Proteins | Compounds |
|---|---|---|
| ajmaline and sarpagine biosynthesis | 1 | 37 |
Research
Studies (32)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (18.75) | 29.6817 |
| 2010's | 17 (53.13) | 24.3611 |
| 2020's | 9 (28.13) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 23.07
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (23.07) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 3 (9.38%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 29 (90.63%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||