Page last updated: 2024-11-12
alstonisine
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
alstonisine: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 14191522 |
CHEMBL ID | 592449 |
SCHEMBL ID | 21832078 |
MeSH ID | M0445134 |
Synonyms (5)
Synonym |
---|
CHEMBL592449 |
alstonisine |
alstonal |
SCHEMBL21832078 |
(1s,2r,7r,9s,10s)-6-acetyl-1'-methylspiro[4-oxa-12-azatricyclo[7.2.1.02,7]dodec-5-ene-10,3'-indole]-2'-one |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (4)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID462410 | Inhibition of alpha-D-[U-14C]glucopyranoside uptake at human SGLT2 expressed in african green monkey COS1 cells at 50 uM after 30 mins by liquid scintillation counting | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Alstiphyllanines E-H, picraline and ajmaline-type alkaloids from Alstonia macrophylla inhibiting sodium glucose cotransporter. |
AID735342 | Cytotoxicity against human KB cells by resazurin assay | 2013 | Journal of natural products, Apr-26, Volume: 76, Issue:4 | Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla. |
AID462409 | Inhibition of alpha-D-[U-14C]glucopyranoside uptake at human SGLT1 expressed in african green monkey COS1 cells at 50 uM after 30 mins by liquid scintillation counting | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Alstiphyllanines E-H, picraline and ajmaline-type alkaloids from Alstonia macrophylla inhibiting sodium glucose cotransporter. |
AID735343 | Antimalarial activity against multidrug-resistant Plasmodium falciparum K1 by [3H]-hypoxanthine incorporation assay | 2013 | Journal of natural products, Apr-26, Volume: 76, Issue:4 | Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (7)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (28.57) | 29.6817 |
2010's | 4 (57.14) | 24.3611 |
2020's | 1 (14.29) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.54
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.54) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 1 (14.29%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 6 (85.71%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |