Assay ID | Title | Year | Journal | Article |
AID1719514 | Induction of autophagosome formation in human HeLa cells assessed as increase in LC3 puncta at 10 uM after 24 hrs in presence of Baf A1 by Alexa Fluor 488 staining based fluorescence microscopic analysis | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719519 | Modulation of autophagy in human HeLa cells assessed as increase in LC3-2 protein level at 10 uM after 24 hrs in presence of chloroquine by Western blot analysis | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719524 | Inhibition of autophagy in human HeLa cells assessed as decrease in cathepsin B at 10 nM after 24 hrs by immunoblot analysis | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719516 | Induction of autophagosome formation in HT-1080 cells assessed as increase in LC3 puncta at 10 uM after 24 hrs by Alexa Fluor 488 staining based fluorescence microscopic analysis | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719515 | Induction of autophagosome formation in human HeLa cells assessed as increase in LC3 puncta at 10 uM after 6 hrs in presence of rapamycin by Alexa Fluor 488 staining based fluorescence microscopic analysis | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719512 | Induction of autophagosome formation in human HeLa cells assessed as increase in LC3 puncta at 10 uM after 24 hrs by Alexa Fluor 488 staining based fluorescence microscopic analysis | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719522 | Inhibition of autophagy in human HeLa cells assessed as increase in lysosomal pH at 10 uM after 24 hrs by LysoTracker Red DND-99 staining based fluorescence microscopic method | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719517 | Induction of autophagosome formation in SK-MEL-28 cells assessed as increase in LC3 puncta at 10 uM after 24 hrs by Alexa Fluor 488 staining based fluorescence microscopic analysis | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719507 | Antiproliferative activity against human HeLa cells assessed as cell viability at 1 uM after 24 hrs by MTT assay relative to control | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719508 | Modulation of autophagy in human HeLa cells assessed as increase in LC3-2 protein level at 1 to 20 uM after 24 hrs by Western blot analysis | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719509 | Inhibition of autophagy in human HeLa cells assessed as increase in P62 protein level at 1 to 20 uM after 24 hrs by Western blot analysis | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719510 | Antiproliferative activity against human HeLa cells assessed as cell viability at 20 uM after 24 hrs by MTT assay relative to control | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719520 | Inhibition of autophagy in human HeLa cells assessed as increase in P62 protein level at 10 uM after 24 hrs in presence of Baf A1 by Western blot analysis | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719518 | Modulation of autophagy in human HeLa cells assessed as increase in LC3-2 protein level at 10 uM after 24 hrs in presence of Baf A1 by Western blot analysis | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719511 | Antiproliferative activity against human HeLa cells assessed as cell viability at 10 uM after 24 hrs by MTT assay relative to control | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
AID1719521 | Inhibition of autophagy in human HeLa cells assessed as increase in P62 protein level at 10 uM after 24 hrs in presence of chloroquine by Western blot analysis | 2021 | Bioorganic & medicinal chemistry, 03-15, Volume: 34 | Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |