| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
pyrogallol
benzenetriol : A triol in which three hydroxy groups are substituted onto a benzene ring. | 2.13 | 1 | 0 | benzenetriol;
phenolic donor | plant metabolite |
aspirin
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5). acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.. acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity. | 2.05 | 1 | 0 | benzoic acids;
phenyl acetates;
salicylates | anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent |
celecoxib
[no description available] | 2.05 | 1 | 0 | organofluorine compound;
pyrazoles;
sulfonamide;
toluenes | cyclooxygenase 2 inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
myristicin
myristicin: asaricin is an isomer; structure; a methylene dioxy version of elemicin; | 2.13 | 1 | 0 | organic molecular entity | metabolite |
tetrahydrofuran
oxolane : A cyclic ether that is butane in which one hydrogen from each methyl group is substituted by an oxygen. | 2.21 | 1 | 0 | cyclic ether;
oxolanes;
saturated organic heteromonocyclic parent;
volatile organic compound | polar aprotic solvent |
malabaricone c
malabaricone C: from maize (Myristica fragrans); structure given in first source | 2.13 | 1 | 0 | butanone | metabolite |
kadsurenone
kadsurenone: platelet-activating factor receptor antagonist from Chinese herbal plant, haifenteng; structure given in first source; RN given refers to (2s-(2alpha,3beta,3aalpha))-isomer | 2.05 | 1 | 0 | benzofurans | |
malabaricone b
malabaricone B: from maize (Myristica fragrans); structure given in first source | 2.13 | 1 | 0 | | |
benzofurans
Benzofurans: Compounds that contain a BENZENE ring fused to a furan ring. | 2.97 | 4 | 0 | | |
grandisin
grandisin: structure given in first source; a lignan isolated from the bark of Cryptocarya crassinervia; RN given refers to ((2alpha,3beta,4alpha,5beta)-(-))-isomer | 2.21 | 1 | 0 | lignan | |
lignans
Lignans: A class of dibenzylbutane derivatives which occurs in higher plants and in fluids (bile, serum, urine, etc.) in man and other animals. These compounds, which have a potential anti-cancer role, can be synthesized in vitro by human fecal flora. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed) | 2.97 | 4 | 0 | | |
caffeic acid
trans-caffeic acid : The trans-isomer of caffeic acid. | 2.05 | 1 | 0 | caffeic acid | geroprotector;
mouse metabolite |
Licarin A
[no description available] | 2.05 | 1 | 0 | benzofurans | |
surinamensin
surinamensin: RN given for (S-(R*,R*-(E)))-isomer; structure in first source | 2.57 | 2 | 0 | phenylpropanoid | |
isoelemicin
isoelemicin: RN given refers to cpd without isomeric designation | 2.13 | 1 | 0 | olefinic compound | |
aldosterone
dehydrodiisoeugenol: an isoeugenol dimer, inhibits lipopolysaccharide-stimulated nuclear factor kappa B activation and cyclooxygenase-2 expression in macrophages; structure in first source | 2.51 | 2 | 0 | | |
ginkgolide b
[no description available] | 2.05 | 1 | 0 | | |
acuminatin
acuminatin: from Epimedium acuminatum; Chemline give RN 41744-39-2 for acuminatin, but the compound has a different structure than the one given in journal. acuminatin : A neolignan that is 5-[(1E)-prop-1-en-1-yl]-2,3-dihydro-1-benzofuran carrying additional 3,4-dimethoxyphenyl, methyl and methoxy substituents at positions 2, 3 and 7 respectively. | 2.05 | 1 | 0 | 1-benzofurans;
dimethoxybenzene;
neolignan;
olefinic compound;
ring assembly | fungal metabolite;
plant metabolite |
machilin a
machilin A: stimulates osteoblast differentiation; isolated from Myristica fragrans; structure in first source | 2.04 | 1 | 0 | | |
macelignan
macelignan: an NSAID with antioxidant, free radical scavenging, and neuroprotective activities; structure in first source | 2.04 | 1 | 0 | lignan | |
cinerin c
cinerin C: isolated from Pleurothyrium cinereum; structure in first source | 2.05 | 1 | 0 | | |
cinerin a
cinerin A: isolated from Pleurothyrium cinereum; structure in first source | 2.05 | 1 | 0 | | |