Compounds > l 643441

Page last updated: 2024-08-01 20:07:36

l 643441

Description

L 643441: structure given in first source [MeSH]

Cross-References

ID Source	ID
PubMed CID	5486883
SCHEMBL ID	4604981
MeSH ID	M0113230

Synonyms (15)

Synonym
l-643441
1-oxo-3-n-[3-[3-(piperidin-1-ylmethyl)phenoxy]propyl]-1,2,5-thiadiazole-3,4-diamine
bdbm50404821
78442-39-4
l-643,441
3-n-(3-(3-(1-piperidinomethyl)phenoxy)propyl)amino-4-amino-1,2,5-thiadiazole-1-oxide
1,2,5-thiadiazole-3,4-diamine, n-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)-, 1-oxide
l 643441
SCHEMBL4604981
3-amino-4-[3-(3-piperidinomethylphenoxy)propylamino]-1,2,5-thiadiazole 1-oxide
DUPAVAVETJQPOR-UHFFFAOYSA-N
3-amino-4-((3-(3-(piperidin-1-ylmethyl)phenoxy)propyl)amino)-1,2,5-thiadiazole 1-oxide
DTXSID60999769
3-amino-4-[(3-{3-[(piperidin-1-yl)methyl]phenoxy}propyl)amino]-1h-1lambda~4~,2,5-thiadiazol-1-one
AKOS040752306

Research

Studies (9)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	9 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	10 (100.00%)	84.16%

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
histamine	5	aralkylamino compound; imidazoles	human metabolite; mouse metabolite; neurotransmitter	1983	1987	39.2	medium	0	5	0	0	0	0
3-methylcholanthrene	1	ortho- and peri-fused polycyclic arene	aryl hydrocarbon receptor agonist; carcinogenic agent	1988	1988	36.0	low	0	1	0	0	0	0
cimetidine	5	aliphatic sulfide; guanidines; imidazoles; nitrile	adjuvant; analgesic; anti-ulcer drug; H2-receptor antagonist; P450 inhibitor	1983	1988	39.2	medium	0	5	0	0	0	0
dimaprit	2	imidothiocarbamic ester		1983	1985	40.0	low	0	2	0	0	0	0
famotidine	3	1,3-thiazoles; guanidines; sulfonamide	anti-ulcer drug; H2-receptor antagonist; P450 inhibitor	1985	1988	37.3	low	0	3	0	0	0	0
omeprazole	1	aromatic ether; benzimidazoles; pyridines; sulfoxide		1985	1985	39.0	low	0	1	0	0	0	0
phenobarbital	1	barbiturates	anticonvulsant; drug allergen; excitatory amino acid antagonist; sedative	1988	1988	36.0	low	0	1	0	0	0	0
aminopyrine	3	pyrazolone; tertiary amino compound	antipyretic; environmental contaminant; non-narcotic analgesic; non-steroidal anti-inflammatory drug; xenobiotic	1983	1985	40.0	low	0	3	0	0	0	0
methacholine chloride	1	quaternary ammonium salt		1987	1987	37.0	low	0	1	0	0	0	0
thiazoles	3	1,3-thiazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene		1985	1988	37.3	low	0	3	0	0	0	0
loxtidine	1	aromatic ether; piperidines; primary alcohol; triazoles	H2-receptor antagonist	1987	1987	37.0	low	0	1	0	0	0	0
triazoles	1	1,2,3-triazole		1987	1987	37.0	low	0	1	0	0	0	0
thiourea	2	one-carbon compound; thioureas; ureas	antioxidant; chromophore	1983	1985	40.0	low	0	2	0	0	0	0
ranitidine	3	C-nitro compound; furans; organic sulfide; tertiary amino compound	anti-ulcer drug; drug allergen; environmental contaminant; H2-receptor antagonist; xenobiotic	1983	1987	39.3	low	0	3	0	0	0	0
rubidium	1	alkali metal atom		1985	1985	39.0	low	0	1	0	0	0	0
sk&f 93479	2			1983	1985	40.0	medium	0	2	0	0	0	0
pentagastrin	1	organic molecular entity		1985	1985	39.0	low	0	1	0	0	0	0
bucladesine	2	3',5'-cyclic purine nucleotide		1984	1987	38.5	low	0	2	0	0	0	0
pyrimidinones	2			1983	1985	40.0	low	0	2	0	0	0	0

Condition	Indicated	Studies	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020

Dosage (1)

Article	Year
Effects of H2-receptor antagonists upon physiological acid secretory states in animals. The Journal of pharmacology and experimental therapeutics, , Volume: 233, Issue:1	1985

Interactions (1)

Article	Year
Comparative effects of H2-receptor antagonists on drug interaction in rats. Drug metabolism and disposition: the biological fate of chemicals, , Volume: 14, Issue:6