Compounds > r 61837
Page last updated: 2024-12-07

r 61837

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

R 61837: antirhinovirus cpd; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID127504
CHEMBL ID1233737
SCHEMBL ID992823
MeSH IDM0160622

Synonyms (22)

Synonym
CHEMBL1233737
r-61837
3-methoxy-6-[4-(m-tolyl)piperazin-1-yl]pyridazine
5-(trifluoromethyl)-3-[3,5-dimethyl-4-[[3-(3-methyl-5-isoxazolyl)propyl]oxy]phenyl]-1,2,4-oxadiazole
r 61837
JEN ,
3-methoxy-6-[4-(3-methylphenyl)-1-piperazinyl]pyridazine
DB08017
3-methoxy-6-[4-(3-methylphenyl)piperazin-1-yl]pyridazine
pyridazine, 3-methoxy-6-(4-(3-methylphenyl)-1-piperazinyl)-
3-methoxy-6-(4-(3-methylphenyl)-1-piperazinyl)pyridazine
100241-46-1
unii-hk76he61aq
hk76he61aq ,
DDOAUTHWSCUHQA-UHFFFAOYSA-N
SCHEMBL992823
DTXSID30143050
r61837
3-methoxy-6-(4-(3-methylphenyl)piperazin-1-yl)pyridazine
Q27097247
3-methoxy-6-(4-(m-tolyl)piperazin-1-yl)pyridazine
AKOS040747335
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1562994Antiviral activity against Rhinovirus at 32 uM relative to control2019European journal of medicinal chemistry, Sep-15, Volume: 178Back to the future: Advances in development of broad-spectrum capsid-binding inhibitors of enteroviruses.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (36.36)18.7374
1990's6 (54.55)18.2507
2000's0 (0.00)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.85

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.85 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index4.42 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.85)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (9.09%)5.53%
Reviews1 (9.09%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (81.82%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
dimethyl sulfoxide
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.. dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.		1.9710sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
sch-48973
[no description available]		3.3110
pleconaril
WIN 63843: structure given in first source		3.3110
win 52035
Win 52035: structure given in first source		3.3110aromatic ether
win 52084
Win 52084: structure given in first source; RN given refers to (+-)-isomer; RN for cpd without isomeric designation not available 7/89		3.3110aromatic ether
piperazine
[no description available]		1.9910azacycloalkane;
piperazines;
saturated organic heteromonocyclic parent		anthelminthic drug
methionine
Methionine: A sulfur-containing essential L-amino acid that is important in many body functions.. methionine : A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4.		1.9810aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
isoxazoles
Isoxazoles: Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.. isoxazole : A monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles.. isoxazoles : Oxazoles in which the N and O atoms are adjacent.		2.6730isoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
disoxaril
disoxaril: antipicornavirus agent		3.7930aromatic ether
pirodavir
pirodavir: antipicornavirus agent; structure given in first source		1.9810
4',6-dichloroflavan
4',6-dichloroflavan: antirhinovirus cpd; structure given in first source		2.3820
win 56291
Win 56291: anti-rhinoviral drug; structure given in first source		1.9810
win 54954
Win 54954: broad-spectrum antipicornavirus drug; structure given in first source		1.9810aromatic ether
chalcone
trans-chalcone : The trans-isomer of chalcone.		2.3820chalconeEC 3.2.1.1 (alpha-amylase) inhibitor
ro 09-0410
Ro 09-0410: structure given in first source		1.9810
piperidines
Piperidines: A family of hexahydropyridines.		1.9810
ConditionIndicatedRelationship StrengthStudiesTrials
Catarrh
Inflammation of a mucous membrane with increased flow of mucous in humans or animals. Catarrh is used mostly in a historical context.		03.3611
Common Cold
A catarrhal disorder of the upper respiratory tract, which may be viral or a mixed infection. It generally involves a runny nose, nasal congestion, and sneezing.		03.3611