Compounds > pyroxasulfone
Page last updated: 2024-11-12

pyroxasulfone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

pyroxasulfone: an herbicide [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11556910
CHEMBL ID2251728
SCHEMBL ID117036
MeSH IDM000599101

Synonyms (28)

Synonym
unii-04xp114422
447399-55-5
pyroxasulfone [iso]
pyroxasulfone
04xp114422 ,
isoxazole, 3-(((5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl)methyl)sulfonyl)-4,5-dihydro-5,5-dimethyl-
isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]methyl]sulfonyl]-4,5-dihydro-5,5-dimethyl-
5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)pyrazol-4-ylmethyl 4,5-dihydro-5,5-dimethyl-1,2-oxazol-3-yl sulfone
pyroxasulfone [mi]
3-(((5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl)methyl)sulfonyl)-4,5-dihydro-5,5-dimethylisoxazole
3-({[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]methyl}sulfonyl)-5,5-dimethyl-4,5-dihydroisoxazole
SCHEMBL117036
CHEMBL2251728
DTXSID4058104
3-(((5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl)methyl)sulfonyl)-5,5-dimethyl-4,5-dihydroisoxazole ,
pyroxasulfone 100 microg/ml in acetonitrile
E76681
3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]methyl]sulfonyl]-4,5-dihydro-5,5-dimethylisoxazole
c12h14f5n3o4s
3-[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methylsulfonyl]-5,5-dimethyl-4h-1,2-oxazole
EX-A3526
isoxazole,3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]methyl]sulfonyl]-4,5-dihydro-5,5-dimethyl-
isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]methyl]sulfonyl]-4,5-dihydro-5,5-dimethyl-; 3-[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)pyrazol-4-ylmethylsulfonyl]-4,5-dihydro-5,5-dimethyl-1,2-oxazole; kih 485; pyro
Q27247713
BS-53232
3-{[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]methanesulfonyl}-5,5-dimethyl-4,5-dihydro-1,2-oxazole
EN300-18849515
CS-0132723

Research Excerpts

Overview

Pyroxasulfone (PYR) is a widely used herbicide. Its effects on non-target organisms, particularly microorganisms, are largely unknown.

ExcerptReferenceRelevance
"Pyroxasulfone (PYS) is an isoxazole herbicide favored for its high activity. "( Accumulation and metabolism of pyroxasulfone in tomato seedlings.
Du, N; Liu, X; Ma, C; Niu, Y; Piao, F; Wang, H; Yan, Z; Zhang, JJ; Zhao, T; Zhou, L, 2023)		2.64
"Pyroxasulfone (PYR) is a widely used herbicide, but its effects on non-target organisms, particularly microorganisms, are largely unknown. "( Impact of pyroxasulfone on sugarcane rhizosphere microbiome and functioning during field degradation.
Bai, L; Cernava, T; Jin, D; Li, W; Ma, Y; Men, J; Wang, Y; Zheng, T, 2023)		2.76
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (61.54)24.3611
2020's5 (38.46)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 54.70

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index54.70 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.60 (4.65)
Search Engine Demand Index88.83 (26.88)
Search Engine Supply Index2.13 (0.95)

This Compound (54.70)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
carbamates
[no description available]		2.8130amino-acid anion
metolachlor
metolachlor: structure given in first source. metolachlor : A racemate that consists of equimolar amounts of (R)- and (S)-metolachlor.. 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)acetamide : An organochlorine compound that is 2-chloroacetamide substituted by a (2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl) group at the nitrogen atom.		7.1310aromatic amide;
benzenes;
ether;
organochlorine compound
triallate
Triallate: A pre-emergence, selective herbicide for the control of wild oats in various crops.		7.0810tertiary amine
trifluralin
Trifluralin: A microtubule-disrupting pre-emergence herbicide.. trifluralin : A substituted aniline that is N,N-dipropylaniline substituted by a nitro groups at positions 2 and 6 and a trifluoromethyl group at position 4. It is an agrochemical used as a pre-emergence herbicide.		7.1710(trifluoromethyl)benzenes;
C-nitro compound;
substituted aniline		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
serine
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.. serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.		2.610L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
isoxazoles
Isoxazoles: Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.. isoxazole : A monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles.. isoxazoles : Oxazoles in which the N and O atoms are adjacent.		4.05120isoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
prosulfocarb
prosulfocarb : A monothiocarbamic ester that is carbamothioic S-acid substituted by two propyl groups at the nitrogen atom and a benzyl group at the the sulfur atom.		2.8130benzenes;
monothiocarbamic ester		environmental contaminant;
herbicide;
xenobiotic
foe 5043
FOE 5043: an oxyacetamide with herbicidal activity; structure given in first source. flufenacet : An aromatic amide that is acetamide in which the amino hydrogens have been replaced by a propan-2-yl and 4-fluorophenyl groups while the methyl hydrogen is replaced by a [5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy group.		2.1310aromatic amide;
monofluorobenzenes;
thiadiazoles		environmental contaminant;
herbicide;
xenobiotic
sirolimus
Sirolimus: A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.. sirolimus : A macrolide lactam isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent.		2.1310antibiotic antifungal drug;
cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
organic heterotricyclic compound;
secondary alcohol		antibacterial drug;
anticoronaviral agent;
antineoplastic agent;
bacterial metabolite;
geroprotector;
immunosuppressive agent;
mTOR inhibitor
chlorophyll a
Chlorophyll: Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organisms.. chlorophyll : A family of magnesium porphyrins, defined by the presence of a fifth ring beyond the four pyrrole-like rings. The rings can have various side chains which usually include a long phytol chain.		2.1310chlorophyll;
methyl ester		cofactor
ConditionIndicatedRelationship StrengthStudiesTrials
Bladder Cancer
[description not available]		02.2510
Urinary Calculi
Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID.		02.2510
Urinary Bladder Neoplasms
Tumors or cancer of the URINARY BLADDER.		02.2510
Hyperplasia
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.		02.2510
Necrosis
The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.		02.2510