Compounds > pseudane ix
Page last updated: 2024-11-11

pseudane ix

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

pseudane IX: isolated from Ruta angustifolia leaves; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
RutagenusA plant genus of the family RUTACEAE. Members contain quinoline alkaloids.[MeSH]RutaceaeA plant family in the order Sapindales that grows in warmer regions and has conspicuous flowers.[MeSH]
Ruta angustifoliaspecies[no description available]RutaceaeA plant family in the order Sapindales that grows in warmer regions and has conspicuous flowers.[MeSH]

Cross-References

ID SourceID
PubMed CID9856730
CHEMBL ID2270128
SCHEMBL ID2126335
SCHEMBL ID21065454
MeSH IDM000605541

Synonyms (26)

Synonym
2-nonyl-1h-quinolin-4-one
SCHEMBL2126335
2-nonylquinolin-4(1h)-one ,
nnq ,
4-quinolinol, 2-nonyl-
2503-81-3
CHEMBL2270128
DTXSID30431883
AKOS027255815
55396-45-7
mfcd28096829
AS-54937
2-nonyl-4-hydroxyquinoline
2-nonyl-4(1h)-quinolone
SCHEMBL21065454
Q27463885
2-nonylquinolin-4-ol
SB70222
W11285
CAA50381
EN300-7415282
PD133700
CS-0667372
HY-W555382
pseudane ix
Z3247535644
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (12)

Assay IDTitleYearJournalArticle
AID1103657Growth inhibition of Fusarium oxysporum at 300 uM after 48 hr by microtiter assay2007The Alkaloids. Chemistry and biology, , Volume: 64Alkyl, aryl, alkylarylquinoline, and related alkaloids.
AID1102116Antifungal activity against Colletotrichum acutatum assessed as growth inhibition at 300 uM after 48 hr by microplate photometric analysis2003Journal of agricultural and food chemistry, Feb-12, Volume: 51, Issue:4
Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid.
AID1102109Antifungal activity against Fusarium oxysporum assessed as growth inhibition at 300 uM after 48 hr by microplate photometric analysis2003Journal of agricultural and food chemistry, Feb-12, Volume: 51, Issue:4
Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid.
AID1674266Cytotoxicity against human HeLa cells assessed as reduction in cell viability2020Journal of natural products, 07-24, Volume: 83, Issue:7
Isolation of 2-Alkyl-4-quinolones with Unusual Side Chains from a Chinese
AID1102097Antifungal activity against Diaporthe ampelina assessed as growth inhibition at 30 uM after 120 hr by microplate photometric analysis2003Journal of agricultural and food chemistry, Feb-12, Volume: 51, Issue:4
Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid.
AID1674264Antibacterial activity against Staphylococcus epidermidis2020Journal of natural products, 07-24, Volume: 83, Issue:7
Isolation of 2-Alkyl-4-quinolones with Unusual Side Chains from a Chinese
AID1102100Antifungal activity against Phomopsis obscurans assessed as growth inhibition at 300 uM after 120 hr by microplate photometric analysis2003Journal of agricultural and food chemistry, Feb-12, Volume: 51, Issue:4
Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid.
AID1102115Antifungal activity against Colletotrichum fragariae assessed as growth inhibition at 30 to 300 uM after 48 hr by microplate photometric analysis2003Journal of agricultural and food chemistry, Feb-12, Volume: 51, Issue:4
Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid.
AID1102101Antifungal activity against Phomopsis obscurans assessed as growth inhibition at 100 uM after 120 hr by microplate photometric analysis2003Journal of agricultural and food chemistry, Feb-12, Volume: 51, Issue:4
Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid.
AID1674265Antibacterial activity against Staphylococcus aureus2020Journal of natural products, 07-24, Volume: 83, Issue:7
Isolation of 2-Alkyl-4-quinolones with Unusual Side Chains from a Chinese
AID1102104Stimulation of Botryotinia fuckeliana growth at 30 uM after 48 hr by microplate photometric analysis2003Journal of agricultural and food chemistry, Feb-12, Volume: 51, Issue:4
Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid.
AID1103659Growth inhibition of Colletotrichum acutatum at 300 uM after 48 hr by microtiter assay2007The Alkaloids. Chemistry and biology, , Volume: 64Alkyl, aryl, alkylarylquinoline, and related alkaloids.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.84

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.84 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.63 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.84)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (20.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational1 (20.00%)0.25%
Other3 (60.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
2-(n-heptyl)-4-hydroxyquinoline n-oxide
2-(n-heptyl)-4-hydroxyquinoline N-oxide: structure. 2-heptyl-4-hydroxyquinoline N-oxide : An inhibitor of the mitochondrial respiratory chain at cytochrome bc1 and of photosynthetic electron flow immediately before cytochrome b559.		2.2510monohydroxyquinoline
5-methoxypsoralen
5-Methoxypsoralen: A linear furanocoumarin that has phototoxic and anti-inflammatory properties, with effects similar to METHOXSALEN. It is used in PUVA THERAPY for the treatment of PSORIASIS.. 5-methoxypsoralen : A 5-methoxyfurocoumarin that is psoralen substituted by a methoxy group at position 5.		2.01105-methoxyfurocoumarin;
organic heterotricyclic compound;
psoralens		hepatoprotective agent;
plant metabolite
methoxsalen
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.. methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.		2.0110aromatic ether;
psoralens		antineoplastic agent;
cross-linking reagent;
dermatologic drug;
photosensitizing agent;
plant metabolite
carbostyril
Quinolones: A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.. quinolin-2(1H)-one : A quinolone that is 1,2-dihydroquinoline substituted by an oxo group at position 2.		2.110monohydroxyquinoline;
quinolone		bacterial xenobiotic metabolite
captan
Captan: One of the phthalimide fungicides.. captan : A dicarboximide that is 3a,4,7,7a-tetrahydrophthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethyl group. A non-systemic fungicide introduced in the 1950s, it is widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops.		3.5320isoindoles;
organochlorine compound;
organosulfur compound;
phthalimide fungicide		antifungal agrochemical
kokusaginine
kokusaginine: antimalarial alkaloid from Teclea afzelii; structure in first source		2.0110organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle
herniarin
herniarin: methoxy analog of umbelliferone; structure. herniarin : A member of the class of coumarins that is coumarin substituted by a methoxy group at position 7.		2.0110coumarinsfluorochrome
benomyl
[no description available]		3.5320aromatic amide;
benzimidazole fungicide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		acaricide;
anthelminthic drug;
antifungal agrochemical;
microtubule-destabilising agent;
tubulin modulator
chalepin
chalepin: furanocoumarin isolated from West African medicinal plant Clausena anisata; RN given refers to cpd without isomeric designation		7.110furanocoumarin
nonyl-4-hydroxyquinoline-n-oxide
[no description available]		2.2510
my 12-62c
MY 12-62c: from Pseudomonas methanica KY4634. 2-heptyl-4-quinolone : A quinolone consisting of quinolin-4(1H)-one carrying a heptyl substituent at position 2.. 2-heptyl-4-hydroxyquinoline : A monohydroxyquinoline that is 4-hydroxyquinoline bearing an additional heptyl substituent at position 2.		2.5720monohydroxyquinoline;
quinolone		antibacterial agent;
iron chelator;
metabolite;
signalling molecule
graveoline
graveoline: structure in first source		2.0110quinolines
7-hydroxycoumarin
7-oxycoumarin: derivatives have anti-oxidant properties. umbelliferone : A hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7.		2.0110hydroxycoumarinfluorescent probe;
food component;
plant metabolite
chiniofon
Hydroxyquinolines: The 8-hydroxy derivatives inhibit various enzymes and their halogenated derivatives, though neurotoxic, are used as topical anti-infective agents, among other uses.		2.1110
4-hydroxycoumarin
2-hydroxychromone: structure		2.0110hydroxycoumarin
ConditionIndicatedRelationship StrengthStudiesTrials
Cystic Fibrosis of Pancreas
[description not available]		02.1110
Infections, Pseudomonas
[description not available]		02.1110
Cystic Fibrosis
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.		02.1110
Pseudomonas Infections
Infections with bacteria of the genus PSEUDOMONAS.		02.1110