Compounds > murrayaquinone a
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murrayaquinone a

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Description

murrayaquinone A: a carbazole alkaloid from Murraya (Rutaceae); structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
MurrayagenusA plant genus of the family RUTACEAE. Members contain murrayanine, koenine, isomahanine, kwangsine, siamenol, murrayafoline A, murrayaquinone A and other cytotoxic carbazolequinones.[MeSH]RutaceaeA plant family in the order Sapindales that grows in warmer regions and has conspicuous flowers.[MeSH]

Cross-References

ID SourceID
PubMed CID127481
CHEMBL ID396171
SCHEMBL ID5396418
MeSH IDM0172241

Synonyms (14)

Synonym
murrayachinon a
NCI60_018838
nsc654274
nsc-654274
murrayaquinone a
CHEMBL396171
3-methyl-9h-carbazole-1,4-dione
100108-66-5
murrayaquinone-a
1h-carbazole-1,4(9h)-dione, 3-methyl-
SCHEMBL5396418
3-methyl-1h-carbazole-1,4(9h)-dione #
XJTABSPWPMYLQX-UHFFFAOYSA-N
DTXSID10142945
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (71)

Assay IDTitleYearJournalArticle
AID376186Growth inhibition of human DMS144 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376193Growth inhibition of human HOP92 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376173Growth inhibition of human SF539 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376148Growth inhibition of human SN12C cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376176Growth inhibition of human SW620 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376195Growth inhibition of human HOP18 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376151Growth inhibition of human ACHN cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376209Growth inhibition of human KB cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376184Growth inhibition of human COLO205 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID1591763Potency index, ratio of 5-fluorouracil IC50 to test compound IC50 for human HL60 cells2019Bioorganic & medicinal chemistry letters, 08-15, Volume: 29, Issue:16
Synthesis of carbazoloquinone derivatives and their antileukemic activity via modulating cellular reactive oxygen species.
AID376203Growth inhibition of human CCRF-CEM cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376190Growth inhibition of human NCI-H322M cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376149Growth inhibition of human RFX393 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376163Growth inhibition of human SK-MEL-28 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376180Growth inhibition of human HCT15 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID1713093Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by WST-1 assay2016European journal of medicinal chemistry, Oct-04, Volume: 121Concise synthesis of carbazole-1,4-quinones and evaluation of their antiproliferative activity against HCT-116 and HL-60 cells.
AID1591765Induction of reactive oxygen species generation in human HL60 cells assessed as increase in extracellular ROS level at 1 uM measured after 2 hrs by NBT dye-based assay2019Bioorganic & medicinal chemistry letters, 08-15, Volume: 29, Issue:16
Synthesis of carbazoloquinone derivatives and their antileukemic activity via modulating cellular reactive oxygen species.
AID376161Growth inhibition of human UACC257 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376162Growth inhibition of human SK-MEL-5 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376201Growth inhibition of human K562 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376154Growth inhibition of human SK-OV-3 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID1591761Cytotoxicity against human HL60 cells assessed as cell viability at 10 uM measured after 48 hrs by CCK8 assay relative to control2019Bioorganic & medicinal chemistry letters, 08-15, Volume: 29, Issue:16
Synthesis of carbazoloquinone derivatives and their antileukemic activity via modulating cellular reactive oxygen species.
AID376198Growth inhibition of human SR cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376200Growth inhibition of human MOLT4 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376187Growth inhibition of human LXFL529 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376158Growth inhibition of human OVACR3 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID1591766Induction of apoptosis in human HL60 cells assessed as chromatin crenation at 1 uM measured after 24 hrs by Hoechst 33342 staining based fluorescence microscopic method2019Bioorganic & medicinal chemistry letters, 08-15, Volume: 29, Issue:16
Synthesis of carbazoloquinone derivatives and their antileukemic activity via modulating cellular reactive oxygen species.
AID376147Growth inhibition of human TK10 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376172Growth inhibition of human SNB19 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376194Growth inhibition of human HOP62 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376202Growth inhibition of human HL60(TB) cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376199Growth inhibition of human RPMI8266 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376155Growth inhibition of human OVACR8 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376178Growth inhibition of human KM12 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID292938Cytotoxicity against mouse P388 cells by MTT assay2007Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1
Structure-activity delineation of quinones related to the biologically active Calothrixin B.
AID1591767Induction of apoptosis in human HL60 cells assessed as chromatin condensation at 1 uM measured after 24 hrs by Hoechst 33342 staining based fluorescence microscopic method2019Bioorganic & medicinal chemistry letters, 08-15, Volume: 29, Issue:16
Synthesis of carbazoloquinone derivatives and their antileukemic activity via modulating cellular reactive oxygen species.
AID376165Growth inhibition of human M19-MEL cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376196Growth inhibition of human EKVX cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376181Growth inhibition of human HCT116 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376157Growth inhibition of human OVACR4 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376210Growth inhibition of human HCT8 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376189Growth inhibition of human NCI-H460 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376177Growth inhibition of human KM20L2 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376156Growth inhibition of human OVACR5 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID292937Cytotoxicity against human HeLa cells by MTT assay2007Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1
Structure-activity delineation of quinones related to the biologically active Calothrixin B.
AID376160Growth inhibition of human UACC62 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376179Growth inhibition of human HT29 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376188Growth inhibition of human NCI-H522 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID1591764Induction of reactive oxygen species generation in human HL60 cells assessed as increase in intracellular ROS level at 1 uM measured after 2 hrs by NBT dye-based assay relative to control2019Bioorganic & medicinal chemistry letters, 08-15, Volume: 29, Issue:16
Synthesis of carbazoloquinone derivatives and their antileukemic activity via modulating cellular reactive oxygen species.
AID376192Growth inhibition of human NCI-H226 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID292939Cytotoxicity against CV1 cells by MTT assay2007Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1
Structure-activity delineation of quinones related to the biologically active Calothrixin B.
AID376175Growth inhibition of human SF268 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376170Growth inhibition of human U251 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376166Growth inhibition of human M14 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376174Growth inhibition of human SF295 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376153Growth inhibition of human 786-0 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID1713092Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay2016European journal of medicinal chemistry, Oct-04, Volume: 121Concise synthesis of carbazole-1,4-quinones and evaluation of their antiproliferative activity against HCT-116 and HL-60 cells.
AID376159Growth inhibition of human IGROV1 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID1591762Cytotoxicity against human HL60 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay2019Bioorganic & medicinal chemistry letters, 08-15, Volume: 29, Issue:16
Synthesis of carbazoloquinone derivatives and their antileukemic activity via modulating cellular reactive oxygen species.
AID1591768Induction of apoptosis in human HL60 cells assessed as chromatin fragmentation at 1 uM measured after 24 hrs by Hoechst 33342 staining based fluorescence microscopic method2019Bioorganic & medicinal chemistry letters, 08-15, Volume: 29, Issue:16
Synthesis of carbazoloquinone derivatives and their antileukemic activity via modulating cellular reactive oxygen species.
AID376171Growth inhibition of human SNB75 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376150Growth inhibition of human CAKI1 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376167Growth inhibition of human MALME-3M cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376185Growth inhibition of human DMS273 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376146Growth inhibition of human UO31 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376164Growth inhibition of human SK-MEL-2 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376197Growth inhibition of human A549 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376183Growth inhibition of human DLD1 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376169Growth inhibition of human XF498 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376191Growth inhibition of human NCI-H23 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
AID376182Growth inhibition of human HCC2998 cells2000Journal of natural products, Jul, Volume: 63, Issue:7
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (10.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's4 (40.00)24.3611
2020's1 (10.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.43

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.43 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.92 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.43)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (9.09%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (90.91%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
cimetidine
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.. cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.		1.9710aliphatic sulfide;
guanidines;
imidazoles;
nitrile		adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
ellipticine
ellipticine : A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.		3.1710indole alkaloid;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound;
polycyclic heteroarene		antineoplastic agent;
plant metabolite
fluorouracil
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.. 5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.		2.2110nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
metoprolol
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.. metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.		1.9710aromatic ether;
propanolamine;
secondary alcohol;
secondary amino compound		antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
geroprotector;
xenobiotic
reserpine
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.. reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.		1.9710alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic
carbazole
carbazole: structure in first source		3.1710carbazole
pyrroles
1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.		3.1710pyrrole;
secondary amine
palladium
Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46.		7.110metal allergen;
nickel group element atom;
platinum group metal atom
camptothecin
NSC 100880: carboxylate (opened lactone) form of camptothecin; RN refers to (S)-isomer; structure given in first source		2.1310delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite
olivacine
olivacine: alkaloid with antitumor & antileukemic activity isolated from Aspidosperma olivaceum; structure; RN given refers to parent cpd		3.1710
murrayafoline a
murrayafoline A: structure in first source		210
calothrixin b
calothrixin B: structure in first source		7.4620
ConditionIndicatedRelationship StrengthStudiesTrials