Page last updated: 2024-12-06

meobentine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

meobentine: RN given refers to parent cpd; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID42765
CHEMBL ID2110972
CHEBI ID134874
SCHEMBL ID309374
SCHEMBL ID309375
SCHEMBL ID11854738
MeSH IDM0102345

Synonyms (27)

Synonym
meobentine
CHEBI:134874
1-[(4-methoxyphenyl)methyl]-2,3-dimethylguanidine
46464-11-3
meobentinum [inn-latin]
1-(p-methoxybenzyl)-2,3-dimethylguqnidine
unii-t91e239z1v
meobentina [inn-spanish]
1-(4-methoxybenzyl)-2,3-dimethylguqnidin
t91e239z1v ,
meobentina
meobentinum
guanidine, n-((4-methoxyphenyl)methyl)-n',n''-dimethyl-
meobentine [inn]
meobentine [mi]
SCHEMBL309374
SCHEMBL309375
SCHEMBL11854738
CHEMBL2110972
smr004703296
MLS006011522
DTXSID30196849
sr-01000945225
SR-01000945225-1
BRD-K85003644-001-01-7
n-[(4-methoxyphenyl)methyl]-n',n''-dimethylguanidine
Q27289826

Research Excerpts

Effects

ExcerptReferenceRelevance
"Meobentine (sulfate) has antifibrillatory and antiarrhythmic activity in canine models. "( The antiarrhythmic activity of meobentine sulfate in man.
Duff, HJ; Oates, JA; Roden, DM; Woosley, RL,
)
1.86

Dosage Studied

ExcerptRelevanceReference
" Adverse reactions led to drug discontinuation in six and dosage reduction in eight patients."( Meobentine sulfate: antiarrhythmic and electrophysiologic effects assessed by programmed electrical stimulation and ambulatory monitoring in patients with complex ventricular tachyarrhythmia. Report of a multicenter evaluation.
Akhtar, M; Anderson, JL; Jueng, P; Long, RA; Platia, EV; Reid, PR; Ruskin, JN; Schaal, SF; Wenger, TL, 1985
)
1.71
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
methoxybenzenesAny aromatic ether that consists of a benzene skeleton substituted with one or more methoxy groups.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (12.50%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (87.50%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]