Page last updated: 2024-11-13

amphidinol 3

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

amphidinol 3: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID46883805
CHEMBL ID1093589
MeSH IDM0404519

Synonyms (2)

Synonym
CHEMBL1093589
amphidinol 3

Research Excerpts

Overview

Amphidinol 3 (AM3) is an anti-fungal polyene extracted from a marine dinoflagellate.

ExcerptReferenceRelevance
"Amphidinol 3 (AM3) is a potent antifungal produced by the dinoflagellate "( Total Synthesis of Amphidinol 3: A General Strategy for Synthesizing Amphidinol Analogues and Structure-Activity Relationship Study.
Ebine, M; Matsumori, N; Oishi, T; Wakamiya, Y, 2020
)
2.33
"Amphidinol 3 (AM3) is an anti-fungal polyene extracted from a marine dinoflagellate. "( Channel Formation and Membrane Deformation via Sterol-Aided Polymorphism of Amphidinol 3.
Iwamoto, M; Kinoshita, M; Matsumori, N; Oiki, S; Shimada, E; Sumino, A, 2017
)
2.13
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (10)

Assay IDTitleYearJournalArticle
AID474963Binding affinity to synthetic palmitoyl-oleoyl-phosphatidylcholine liposome assessed as overall equilibrium association constant at 10 uM by surface plasmon resonance assay in presence of 5% cholesterol2010Bioorganic & medicinal chemistry letters, Apr-01, Volume: 20, Issue:7
Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance.
AID474960Binding affinity to synthetic palmitoyl-oleoyl-phosphatidylcholine liposome assessed as association constant for compound- PPC liposome reorientation complex at 10 uM by surface plasmon resonance assay in presence of 5% cholesterol2010Bioorganic & medicinal chemistry letters, Apr-01, Volume: 20, Issue:7
Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance.
AID474958Binding affinity to synthetic palmitoyl-oleoyl-phosphatidylcholine liposome at 10 uM by surface plasmon resonance assay in presence of 5% ergosterol2010Bioorganic & medicinal chemistry letters, Apr-01, Volume: 20, Issue:7
Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance.
AID474965Permeability across egg phosphatidylcholine membrane2010Bioorganic & medicinal chemistry letters, Apr-01, Volume: 20, Issue:7
Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance.
AID474959Binding affinity to synthetic palmitoyl-oleoyl-phosphatidylcholine liposome assessed as association constant for compound- PPC liposome reorientation complex at 10 uM by surface plasmon resonance assay2010Bioorganic & medicinal chemistry letters, Apr-01, Volume: 20, Issue:7
Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance.
AID474956Binding affinity to synthetic palmitoyl-oleoyl-phosphatidylcholine liposome at 10 uM by surface plasmon resonance assay2010Bioorganic & medicinal chemistry letters, Apr-01, Volume: 20, Issue:7
Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance.
AID474962Binding affinity to synthetic palmitoyl-oleoyl-phosphatidylcholine liposome assessed as overall equilibrium association constant at 10 uM by surface plasmon resonance assay2010Bioorganic & medicinal chemistry letters, Apr-01, Volume: 20, Issue:7
Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance.
AID474961Binding affinity to synthetic palmitoyl-oleoyl-phosphatidylcholine liposome assessed as association constant for compound- PPC liposome reorientation complex at 10 uM by surface plasmon resonance assay in presence of 5% ergosterol2010Bioorganic & medicinal chemistry letters, Apr-01, Volume: 20, Issue:7
Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance.
AID474957Binding affinity to synthetic palmitoyl-oleoyl-phosphatidylcholine liposome at 10 uM by surface plasmon resonance assay in presence of 5% cholesterol2010Bioorganic & medicinal chemistry letters, Apr-01, Volume: 20, Issue:7
Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance.
AID474964Binding affinity to synthetic palmitoyl-oleoyl-phosphatidylcholine liposome assessed as overall equilibrium association constant at 10 uM by surface plasmon resonance assay in presence of 5% ergosterol2010Bioorganic & medicinal chemistry letters, Apr-01, Volume: 20, Issue:7
Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (30)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (50.00)29.6817
2010's14 (46.67)24.3611
2020's1 (3.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (3.33%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other29 (96.67%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]