Page last updated: 2024-10-24
regulation of synaptic transmission, glycinergic
Definition
Target type: biologicalprocess
Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. [GOC:dms, GOC:dph]
Proteins (1)
| Protein | Definition | Taxonomy |
|---|---|---|
| Sodium- and chloride-dependent glycine transporter 1 | A sodium- and chloride-dependent glycine transporter 1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P48067] | Homo sapiens (human) |
Compounds (8)
| Compound | Definition | Classes | Roles |
|---|---|---|---|
| glycine | alpha-amino acid; amino acid zwitterion; proteinogenic amino acid; serine family amino acid | EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor; fundamental metabolite; hepatoprotective agent; micronutrient; neurotransmitter; NMDA receptor agonist; nutraceutical | |
| sarcosine | cocobetaine: N-alkyl-betaine; cause of shampoo dermatitis | N-alkylglycine; N-alkylglycine zwitterion; N-methyl-amino acid; N-methylglycines | Escherichia coli metabolite; glycine receptor agonist; glycine transporter 1 inhibitor; human metabolite; mouse metabolite |
| hinokinin | hinokinin : A lignan that is dihydrofuran-2(3H)-one (gamma-butyrolactone) substituted by a 3,4-methylenedioxybenzyl group at positions 3 and 4 (the 3R,4R-diastereoisomer). hinokinin: suppresses expression of both HBsAg and HBeAg | benzodioxoles; gamma-lactone; lignan | trypanocidal drug |
| org 24598 | org 24598: structure in first source | ||
| n-oleoylglycine | N-oleoylglycine : A fatty acid derivative that is the 9Z-octadecenoyl derivative of glycine. It is believed to be an intermediate in oleamide biosynthesis. oleoylglycine: long chain fatty acyl glycine | fatty amide; N-acylglycine 18:1 | metabolite |
| alx 5407 | biphenyls | ||
| alx 1393 | ALX 1393: a GlyT2 inhibitor | ||
| rg 1678 | (4-(3-fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl)(5-methanesulfonyl-2-(2,2,2-trifluoro-1-methylethoxy)phenyl)methanone: a GlyT1 inhibitor; structure in first source |