Page last updated: 2024-12-06
1-piperideine
Description
1-Piperideine is a heterocyclic compound with a six-membered ring containing one nitrogen atom. It is an important intermediate in the synthesis of various pharmaceuticals and other organic compounds. The compound is also a substrate for a number of enzymes, including monoamine oxidase, which is responsible for the breakdown of neurotransmitters such as dopamine, serotonin, and norepinephrine. 1-Piperideine has been studied for its potential therapeutic applications, particularly in the treatment of Parkinson's disease, Alzheimer's disease, and depression. '
1-piperideine: RN given refers to parent cpd; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 68161 |
| CHEBI ID | 47858 |
| MeSH ID | M0127687 |
Synonyms (17)
| Synonym |
|---|
| delta1-piperideine |
| .delta.1-piperideine |
| inchi=1/c5h9n/c1-2-4-6-5-3-1/h4h,1-3,5h |
| pyridine, 2,3,4,5-tetrahydro- |
| 2,3,4,5-tetrahydropyridine |
| C06181 |
| piperideine |
| 1-piperideine |
| delta(1)-piperideine |
| 505-18-0 |
| CHEBI:47858 |
| 2,3,4,5,-tetrahydropyridine |
| dehydropiperidine |
| DTXSID20198514 |
| Q27104595 |
| 10-acetyl-phenoxazine-3,7-dioldiacetate |
| piperideine, trimere |
Drug Classes (1)
| Class | Description |
|---|
| piperideine | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (7)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 21.39
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 21.39 (24.57) | | Research Supply Index | 2.08 (2.92) | | Research Growth Index | 4.18 (4.65) | | Search Engine Demand Index | 18.60 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |