dichlofenthion

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID Source	ID
PubMed CID	7328
CHEMBL ID	1396626
CHEBI ID	81730
SCHEMBL ID	117873
MeSH ID	M0057757

Synonyms (96)

Synonym
nsc3130
phosphorothioic acid, o-(2,4-dichlorophenyl) o,o-diethyl ester
hexanema
o,4-dicloro-fenil)-monotiofosfato
o,4-dichlor-phenyl-monothiophosphat
o,4-dichlorophenyl) thiophosphate
2,4-dichlorophenyl diethyl phosphorothionate
dichlofenthion
o,4-dichlorophenyl) phosphorothioate
thiophosphate de o-2,o-diethyle
ent 17,470
o-(2,o-diethyl phosphorothioate
vc 13
wln: gr cg dops & o2 & o2
nemacide
v-c 13
nsc-52964
97-17-6
o-2,o-diethyl phosphorothioate
o,4-dichloor-fenyl)-monothiofosfaat
v-c 1-13
phosphorothioic acid,4-dichlorophenyl)-o,o-diethyl ester
dichlofention
diethyl 2,4-dichlorophenyl phosphorothionate
o,4-dichlorophenyl)phosphorothioate
phenol,4-dichloro-, o-ester with o,o-diethyl phosphorothioate
v-cl 13
dichlorofenthion
v-c-13
tri-vc 13
phosphorothioic acid,4-dichlorophenyl) o,o-diethyl ester
nsc52964
vc-13 nemacide
mobilawn
dichlofenthion [ansi]
einecs 202-564-5
o,o-diaethyl-o-2,4-dichlor-phenyl-monothiophosphat [german]
2,4-dichloro-phenyl diethyl phosphorothionate
ecp (pesticide)
ai3-17470
phenol, 2,4-dichloro-, o-ester with o,o-diethyl phosphorothioate
epa pesticide chemical code 028601
o,o-diaethyl-o-2,4-dichlorphenyl-thionophosphat [german]
thiophosphate de o-2,4-dichlorophenyle et de o,o-diethyle [french]
ent 17470
nsc 52964
hsdb 1576
nemacide vc-13
o,o-dietil-o-(2,4-dicloro-fenil)-monotiofosfato [italian]
caswell no. 321
brn 1993440
vc13 nemacide
o-(2,4-dichlorophenyl)-o,o-diethyl phosphorothioic acid
o-2,4-dichlorophenyl o,o-diethyl phosphorothioate
o,o-diethyl o-(2,4-dichlorophenyl) phosphorothioate
o,o-diethyl-o-(2,4-dichloor-fenyl)-monothiofosfaat [dutch]
o,o-diethyl o-2,4-dichlorophenyl thiophosphate
NCGC00166316-01
NCGC00166316-02
thiophosphate de o-2,4-dichlorophenyle et de o,o-diethyle
dichlofenthion [ban]
o,o-diaethyl-o-2,4-dichlorphenyl-thionophosphat
o,o-diaethyl-o-2,4-dichlor-phenyl-monothiophosphat
o,o-diethyl-o-(2,4-dichloor-fenyl)-monothiofosfaat
unii-64234gt8tt
dichlofenthion [ansi:iso]
o,o-dietil-o-(2,4-dicloro-fenil)-monotiofosfato
64234gt8tt ,
C18398
NCGC00255058-01
dtxcid6020274
cas-97-17-6
tox21_301160
dtxsid8040274 ,
CHEMBL1396626
chebi:81730 ,
diclofenthion
dichlorfenthion
FT-0603082
AKOS015902498
SCHEMBL117873
o-(2,4-dichlorophenyl) o,o-diethyl thiophosphate #
o-(2,4-dichlorophenyl) o,o-diethyl phosphorothioate
o,o-diethyl o-(2,4-dichlorophenyl) thiophosphate
o-(2,4-dichlorophenyl)o,o-diethylphosphorothionate
dichlofenthion [hsdb]
dichlofenthion [iso]
dichlofenthion [mi]
dichlofenthion [mart.]
sr-01000883721
SR-01000883721-1
dichlofenthion, pestanal(r), analytical standard
dichlofenthion 10 microg/ml in cyclohexane
Q3026533
(2,4-dichlorophenoxy)-diethoxy-sulfanylidene-lambda5-phosphane
dichlofenthion 1000 microg/ml in acetone

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

Class	Description
organic thiophosphate
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (11)

Potency Measurements

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	Homo sapiens (human)	Potency	56.2341	0.0040	23.8416	100.0000	AID485290
acetylcholinesterase	Homo sapiens (human)	Potency	28.2576	0.0025	41.7960	15,848.9004	AID1347398
phosphopantetheinyl transferase	Bacillus subtilis	Potency	19.9526	0.1413	37.9142	100.0000	AID1490
GLI family zinc finger 3	Homo sapiens (human)	Potency	54.4827	0.0007	14.5928	83.7951	AID1259369
AR protein	Homo sapiens (human)	Potency	20.3246	0.0002	21.2231	8,912.5098	AID1259243; AID1259247
nuclear receptor subfamily 1, group I, member 3	Homo sapiens (human)	Potency	18.1110	0.0010	22.6508	76.6163	AID1224838; AID1224839; AID1224893
progesterone receptor	Homo sapiens (human)	Potency	21.6899	0.0004	17.9460	75.1148	AID1346795
estrogen nuclear receptor alpha	Homo sapiens (human)	Potency	54.4827	0.0002	29.3054	16,493.5996	AID743079
aryl hydrocarbon receptor	Homo sapiens (human)	Potency	15.5345	0.0007	23.0674	1,258.9301	AID743085; AID743122
vitamin D3 receptor isoform VDRA	Homo sapiens (human)	Potency	50.1187	0.3548	28.0659	89.1251	AID504847
thyroid hormone receptor beta isoform 2	Rattus norvegicus (Norway rat)	Potency	68.5896	0.0003	23.4451	159.6830	AID743067
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	3 (75.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 27.14

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	27.14 (24.57)
Research Supply Index	1.79 (2.92)
Research Growth Index	4.32 (4.65)
Search Engine Demand Index	36.32 (26.88)
Search Engine Supply Index	2.71 (0.95)

This Compound (27.14)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	1 (20.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	4 (80.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
carbamates [no description available]	1.95	1	amino-acid anion
diazinon Diazinon: A cholinesterase inhibitor that is used as an organothiophosphorus insecticide.. diazinon : A member of the class of pyrimidines that is pyrimidine carrying an isopropyl group at position 2, a methyl group at position 6 and a (diethoxyphosphorothioyl)oxy group at position 4.	1.95	1	organic thiophosphate; pyrimidines	acaricide; agrochemical; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; environmental contaminant; nematicide; xenobiotic
fenthion Fenthion: Potent cholinesterase inhibitor used as an insecticide and acaricide.. fenthion : An organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen atom of the hydroxy group is replaced by a 3-methyl-4-(methylsulfanyl)phenyl group. It exhibits acaricidal and insecticidal activities.	1.95	1	organic thiophosphate	acaricide; agrochemical; avicide; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; insecticide
chlorfenvinphos Chlorfenvinphos: An organophosphorus cholinesterase inhibitor that is used as an insecticide and an acaricide.	1.95	1	dichlorobenzene; organic phosphate; organochlorine acaricide; organochlorine insecticide; organophosphate insecticide	agrochemical; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor
titanium Titanium: A dark-gray, metallic element of widespread distribution but occurring in small amounts with atomic number, 22, atomic weight, 47.867 and symbol, Ti; specific gravity, 4.5; used for fixation of fractures.	2.06	1	titanium group element atom
atropine tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate : A tropane alkaloid that is (1R,5)-8-methyl-8-azabicyclo[3.2.1]octane substituted by a (3-hydroxy-2-phenylpropanoyl)oxy group at position 3.	1.95	1
dextrothyroxine [no description available]	1.97	1

Condition	Relationship Strength	Studies
Bovine Diseases [description not available]	1.97	1
Maggot Infestations [description not available]	1.97	1
Chrysomya bezziana Infection [description not available]	1.97	1

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