Assay ID | Title | Year | Journal | Article |
AID1477687 | Selectivity ratio of IC50 for His tagged recombinant BRD4 bromodomain 1 (unknown origin) to IC50 for His tagged recombinant CBP (unknown origin) | 2017 | Journal of medicinal chemistry, 12-28, Volume: 60, Issue:24
| A Unique Approach to Design Potent and Selective Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) Inhibitors. |
AID1171197 | Antimicrobial activity against Escherichia coli 1116 after 24 to 48 hrs by serial dilution method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1101160 | Fungicidal activity against Cryphonectria parasitica assessed as inhibition of fungal growth at 25 ug after 7 days | 2000 | Journal of agricultural and food chemistry, Oct, Volume: 48, Issue:10
| Isolation and characterization of fungal inhibitors from Epichloë festucae. |
AID1885212 | Inverse agonist activity at Nurr1 (unknown origin) assessed as remaining activity relative to control | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14
| Medicinal Chemistry and Chemical Biology of Nurr1 Modulators: An Emerging Strategy in Neurodegeneration. |
AID1477685 | Inhibition of His tagged recombinant CBP (unknown origin) by TR-FRET assay | 2017 | Journal of medicinal chemistry, 12-28, Volume: 60, Issue:24
| A Unique Approach to Design Potent and Selective Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) Inhibitors. |
AID1171196 | Antimicrobial activity against Paenibacillus polymyxa 36 after 24 to 48 hrs by serial dilution method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1171208 | Cytotoxicity against human PC3 cells by MTT assay | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1477704 | Inhibition of His tagged recombinant CBP (unknown origin) at 50 uM by HTS assay | 2017 | Journal of medicinal chemistry, 12-28, Volume: 60, Issue:24
| A Unique Approach to Design Potent and Selective Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) Inhibitors. |
AID1372697 | Inhibition of mushroom tyrosinase using tyrosine as substrate pretreated for 5 mins followed by substrate addition measured after 20 mins by ELISA | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2
| Characterization of tyrosinase inhibitory constituents from the aerial parts of Humulus japonicus using LC-MS/MS coupled online assay. |
AID1171202 | Antimicrobial activity against Wickerhamomyces anomalus 6766 after 24 to 48 hrs by serial dilution method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1171209 | Cytotoxicity against human KB3-1 cells by MTT assay | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1171199 | Antimicrobial activity against Pseudomonas aeruginosa 50071 after 24 to 48 hrs by serial dilution method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1780506 | Inverse agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing firefly luciferase assessed as luciferase activity by hybrid reporter gene assay | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20
| Development and Profiling of Inverse Agonist Tools for the Neuroprotective Transcription Factor Nurr1. |
AID1171200 | Antimicrobial activity against Saccharomyces cerevisiae 70449 after 24 to 48 hrs by serial dilution method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1885211 | Inverse agonist activity at Nurr1 (unknown origin) | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14
| Medicinal Chemistry and Chemical Biology of Nurr1 Modulators: An Emerging Strategy in Neurodegeneration. |
AID1171198 | Antimicrobial activity against Chromobacterium violaceum 30191 after 24 to 48 hrs by serial dilution method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1171211 | Cytotoxicity against human A549 cells by MTT assay | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1101161 | Fungicidal activity against Cryphonectria parasitica assessed as inhibition of fungal growth at 50 ug after 7 days | 2000 | Journal of agricultural and food chemistry, Oct, Volume: 48, Issue:10
| Isolation and characterization of fungal inhibitors from Epichloë festucae. |
AID1171194 | Antimicrobial activity against Staphylococcus aureus 346 after 24 to 48 hrs by serial dilution method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1171212 | Cytotoxicity against human SKOV3 cells by MTT assay | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1780507 | Inverse agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing firefly luciferase assessed as remaining activity by hybrid reporter gene assay relative to control | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20
| Development and Profiling of Inverse Agonist Tools for the Neuroprotective Transcription Factor Nurr1. |
AID1171205 | Cytotoxicity against mouse L929 cells by MTT assay | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1101159 | Fungicidal activity against Cryphonectria parasitica assessed as inhibition of fungal growth at 12.5 ug after 7 days | 2000 | Journal of agricultural and food chemistry, Oct, Volume: 48, Issue:10
| Isolation and characterization of fungal inhibitors from Epichloë festucae. |
AID1171201 | Antimicrobial activity against Candida albicans 1665 after 24 to 48 hrs by serial dilution method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1171195 | Antimicrobial activity against Mycobacterium diernhoferi 43542 after 24 to 48 hrs by serial dilution method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1171204 | Antimicrobial activity against Mucor hiemalis 2656 after 24 to 48 hrs by serial dilution method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1171210 | Cytotoxicity against human MCF7 cells by MTT assay | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1101162 | Fungicidal activity against Cryphonectria parasitica assessed as inhibition of fungal growth at 100 ug after 7 days | 2000 | Journal of agricultural and food chemistry, Oct, Volume: 48, Issue:10
| Isolation and characterization of fungal inhibitors from Epichloë festucae. |
AID1171193 | Antimicrobial activity against Nocardia sp. 43069 after 24 to 48 hrs by serial dilution method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1477686 | Inhibition of His tagged recombinant BRD4 bromodomain 1 (unknown origin) by TR-FRET assay | 2017 | Journal of medicinal chemistry, 12-28, Volume: 60, Issue:24
| A Unique Approach to Design Potent and Selective Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) Inhibitors. |
AID1171203 | Antimicrobial activity against Trichosporon oleaginosus 11815 after 24 to 48 hrs by serial dilution method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11
| Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6
| A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | | | |
AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
| High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |