1-(3-phenoxypropyl)-3-indolecarbonitrile

1-(3-phenoxypropyl)-3-indolecarbonitrile is a chemical compound with the following structure:

**Structure:**

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**Importance in Research:**

This compound is a **potent and selective inhibitor of the enzyme histone deacetylase 6 (HDAC6)**. HDAC6 is a key regulator of cellular processes such as protein degradation, cell survival, and immune responses.

Here's why this compound is important in research:

* **Drug development for cancer and other diseases:** HDAC6 inhibition has shown promising therapeutic potential in various disease models, including cancer, neurodegenerative disorders, and inflammatory diseases. 1-(3-phenoxypropyl)-3-indolecarbonitrile, due to its potency and selectivity, serves as a valuable tool for investigating the therapeutic potential of HDAC6 inhibition.
* **Understanding HDAC6 function:** This compound, along with other HDAC6 inhibitors, allows researchers to study the specific roles of HDAC6 in different cellular pathways. By inhibiting HDAC6, they can observe the downstream effects and gain insights into its function in various biological processes.
* **Lead compound for new drug development:** 1-(3-phenoxypropyl)-3-indolecarbonitrile can serve as a starting point for designing new and improved HDAC6 inhibitors with potentially better therapeutic properties. Researchers can modify its structure to enhance its potency, selectivity, or pharmacokinetic profile.

**However, it's important to note:**

* This compound is a research tool and not yet approved for clinical use.
* More research is needed to fully understand its therapeutic potential and safety profile before it can be considered for clinical applications.

**In summary, 1-(3-phenoxypropyl)-3-indolecarbonitrile is a valuable tool for research due to its ability to selectively inhibit HDAC6, thus enabling studies on its role in disease pathogenesis and potential therapeutic applications.**