Compounds > l 651392
Page last updated: 2024-09-03

l 651392 and indomethacin

l 651392 has been researched along with indomethacin in 6 studies

Compound Research Comparison

Studies
(l 651392)		Trials
(l 651392)		Recent Studies (post-2010)
(l 651392)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
310029,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomyl 651392 (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Castro, GA; Myers, S; Zhang, S1
Phillips, C1
Castro, GA; Zhang, S1
Häyry, P; Leszczynski, D1
Mattila, P; Renkonen, R1
Abbate, M; Bertani, T; Cucchi, M; Delaini, F; Perico, N; Remuzzi, G; Tagliaferri, M1

Other Studies

6 other study(ies) available for l 651392 and indomethacin

ArticleYear
Inhibition of anaphylaxis-evoked intestinal fluid secretion by the dual application of an H1 antagonist and cyclooxygenase inhibitor.
    Gastroenterology, 1991, Volume: 100, Issue:4

    Topics: Analysis of Variance; Anaphylaxis; Animals; Antigens, Helminth; Chlorides; Diphenhydramine; Drug Synergism; Histamine H1 Antagonists; Histamine Release; Immunization; Indomethacin; Intestinal Secretions; Intestine, Small; Lipoxygenase Inhibitors; Male; Phenothiazines; Prostaglandins; Rats; Rats, Inbred Strains; Trichinella; Trichinellosis

1991
Induction of leukotriene production before antigen challenge enhances antibody affinity in genetically selected mice.
    Cellular immunology, 1991, Volume: 136, Issue:1

    Topics: Animals; Antibody Affinity; Dinoprostone; Histocompatibility Antigens Class II; Indomethacin; Interleukin-1; Leukotrienes; Macrophages; Mice; Phenothiazines; T-Lymphocytes

1991
Involvement of type I hypersensitivity in rapid rejection of Trichinella spiralis from adult rats.
    International archives of allergy and applied immunology, 1990, Volume: 93, Issue:2-3

    Topics: Animals; Diphenhydramine; Hypersensitivity; Immunization, Passive; Indomethacin; Intestinal Mucosa; Intestines; Male; Phenothiazines; Rats; Rats, Inbred Strains; Serotonin; Trichinella

1990
Eicosanoids are regulatory molecules in gamma-interferon-induced endothelial antigenicity and adherence for leucocytes.
    FEBS letters, 1989, Jan-02, Volume: 242, Issue:2

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Cell Adhesion; Eicosanoic Acids; Endothelium, Vascular; Histocompatibility Antigens Class II; In Vitro Techniques; Indomethacin; Interferon-gamma; Leukocytes; Methylprednisolone; Phenothiazines; Prostaglandin-Endoperoxide Synthases; Rats

1989
Gamma-interferon induces prostacyclin and prostaglandin but not lipoxygenase product synthesis in rat endothelial cells.
    Immunology letters, 1989, Volume: 22, Issue:1

    Topics: Animals; Cells, Cultured; Chromatography, Thin Layer; Eicosanoic Acids; Endothelium, Vascular; Epoprostenol; Indomethacin; Interferon-gamma; Lipoxygenase; Methylprednisolone; Myocardium; Phenothiazines; Prostaglandins E; Rats; Thromboxane B2

1989
Effect of platelet-activating factor and its specific receptor antagonist on glomerular permeability to proteins in isolated perfused rat kidney.
    Laboratory investigation; a journal of technical methods and pathology, 1988, Volume: 58, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antioxidants; Basement Membrane; Cell Membrane Permeability; Cyclooxygenase Inhibitors; Furans; Glomerular Filtration Rate; Indomethacin; Kidney Glomerulus; Lipoxygenase Inhibitors; Male; Microscopy, Electron; Perfusion; Phenothiazines; Platelet Activating Factor; Proteins; Proteinuria; Pyrazoles; Rats; Rats, Inbred Strains; Vascular Resistance

1988