Compounds > aj 76
Page last updated: 2024-09-03

aj 76 and pimozide

aj 76 has been researched along with pimozide in 3 studies

Compound Research Comparison

Studies
(aj 76)		Trials
(aj 76)		Recent Studies (post-2010)
(aj 76)		Studies
(pimozide)		Trials
(pimozide)		Recent Studies (post-2010) (pimozide)
37021,837143152

Protein Interaction Comparison

ProteinTaxonomyaj 76 (IC50)pimozide (IC50)
XBP1Homo sapiens (human)10
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.201
Ubiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)2
Potassium channel subfamily K member 2Homo sapiens (human)1.8
Bile salt export pumpHomo sapiens (human)10
Sodium channel protein type 2 subunit alphaRattus norvegicus (Norway rat)0.34
ATP-dependent translocase ABCB1Homo sapiens (human)2.2
Cytochrome P450 3A4Homo sapiens (human)9.7
DRattus norvegicus (Norway rat)0.0004
D(3) dopamine receptorRattus norvegicus (Norway rat)0.0004
ATP-dependent translocase ABCB1Mus musculus (house mouse)4.9
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.0004
D(4) dopamine receptorRattus norvegicus (Norway rat)0.0004
Mu-type opioid receptorHomo sapiens (human)0.372
Sodium channel protein type 1 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 4 subunit alphaHomo sapiens (human)0.054
Delta-type opioid receptorHomo sapiens (human)3.76
Kappa-type opioid receptorHomo sapiens (human)0.99
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0004
Sodium channel protein type 7 subunit alphaHomo sapiens (human)0.054
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.201
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.152
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.201
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.201
Sodium channel protein type 5 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 9 subunit alphaHomo sapiens (human)0.054
WD repeat-containing protein 48Homo sapiens (human)2
Sodium channel protein type 2 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 3 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 11 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 8 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 10 subunit alphaHomo sapiens (human)0.054

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrieux, M; Besançon, R; Giros, B; Martres, MP; Pilon, C; Schwartz, JC; Sokoloff, P1
Bouthenet, ML; Giros, B; Martres, MP; Schwartz, JC; Sokoloff, P1
Griffon, N; Pilon, C; Sautel, F; Schwartz, JC; Sokoloff, P1

Other Studies

3 other study(ies) available for aj 76 and pimozide

ArticleYear
Pharmacology of human dopamine D3 receptor expressed in a mammalian cell line: comparison with D2 receptor.
    European journal of pharmacology, 1992, Apr-10, Volume: 225, Issue:4

    Topics: Animals; Chlorides; CHO Cells; Cricetinae; Dopamine; Dopamine Agents; Dopamine Antagonists; Guanylyl Imidodiphosphate; Humans; Lithium; Lithium Chloride; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Sodium Chloride; Sulpiride; Transfection

1992
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.
    Nature, 1990, Sep-13, Volume: 347, Issue:6289

    Topics: Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line; Cloning, Molecular; Cricetinae; DNA; DNA Restriction Enzymes; Dopamine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Nucleic Acid Hybridization; Polymerase Chain Reaction; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Sequence Homology, Nucleic Acid; Tissue Distribution

1990
Antipsychotics with inverse agonist activity at the dopamine D3 receptor.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:10

    Topics: Animals; Antipsychotic Agents; Calcium; CHO Cells; Clozapine; Colforsin; Cricetinae; Cyclic AMP; DNA Replication; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Flupenthixol; Glioma; Haloperidol; Humans; Hybrid Cells; Naphthalenes; Neuroblastoma; Pertussis Toxin; Phenothiazines; Pimozide; Pyrrolidines; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D3; Recombinant Proteins; Risperidone; Salicylamides; Second Messenger Systems; Sulpiride; Tetrahydronaphthalenes; Tumor Cells, Cultured; Virulence Factors, Bordetella

1996