| Assay ID | Title | Year | Journal | Article |
|---|
| AID552107 | Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as effect on serotonin-induced response | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome. |
| AID552302 | Inhibition of human CYP2C9 | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome. |
| AID552297 | Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as decrease in 100 uM 5-chloroindole-induced increase in intracellular calcium release at 3 uM relative to 5-HT | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome. |
| AID552110 | Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells at 3 uM relative to 5HT | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome. |
| AID552304 | Inhibition of human CYP2D6 | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome. |
| AID552303 | Inhibition of human CYP2C19 | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome. |
| AID552301 | Inhibition of human CYP2B6 | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome. |
| AID552300 | Inhibition of human CYP1A2 | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome. |
| AID552309 | Partial agonist activity at 5HT3 receptor in po dosed mouse assessed inhibition of serotonin-induced bradycardia administered 1 hr before serotonin challenge by von Bezold-Jarisch reflex test | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome. |
| AID552299 | Inhibition of human CYP3A4 | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome. |
| AID552305 | Intrinsic clearance in human liver microsomes assessed per mg of protein | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome. |
| AID552111 | Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as decrease in 10 uM 5-chloroindole-induced increase in intracellular calcium release | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1
| Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |