Page last updated: 2024-11-07

phenylalanylglutamate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

phenylalanylglutamate: RN given refers to all L-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Phe-Glu : A dipeptide formed from L-phenylalanine and L-glutamic acid residues. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID151134
CHEMBL ID476830
CHEBI ID74712
SCHEMBL ID3048911
MeSH IDM0122714

Synonyms (26)

Synonym
phenylalanylglutamate
(2s)-2-[[(2s)-2-amino-3-phenylpropanoyl]amino]pentanedioic acid
CHEMBL476830
chebi:74712 ,
3617-45-6
phe-glu
l-glutamic acid, n-l-phenylalanyl-
AKOS010407206
n-l-phenylalanyl-l-glutamic acid
l-phenylalanyl-l-glutamic acid
phenylalanylglutamic acid
l-phe-l-glu
h-phe-glu-oh
SCHEMBL3048911
DTXSID70189735
mfcd00037300
l-phenylalanyl-l-glutamate
phenylalanine-glutamate dipeptide
phenylalanine glutamate dipeptide
fe dipeptide
f-e dipeptide
phenylalanyl-glutamic acid
Q27144851
l-glutamic acid, l-phenylalanyl-
(2s)-2-[(2s)-2-amino-3-phenylpropanamido]pentanedioic acid
(s)-2-((s)-2-amino-3-phenylpropanamido)pentanedioic acid
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
metaboliteAny intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
dipeptideAny molecule that contains two amino-acid residues connected by peptide linkages.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID396056Antagonist activity at human PPARgamma receptor expressed in Saccharomyces cerevisiae AH109 co-transfected with mouse CBP assessed as inhibition of rosiglitazone-induced LBD-CBP interaction at 10 uM by alpha-galactosidase based yeast two hybrid assay2008European journal of medicinal chemistry, Dec, Volume: 43, Issue:12
Tryptophan-containing dipeptide derivatives as potent PPARgamma antagonists: design, synthesis, biological evaluation, and molecular modeling.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.53

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.53 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.53)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]