oleuropeic acid: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 188320 |
| CHEMBL ID | 4796626 |
| MeSH ID | M0376035 |
| Synonym |
|---|
| oleuropeic acid |
| 5027-76-9 |
| (4s)-4-(2-hydroxypropan-2-yl)cyclohexene-1-carboxylic acid |
| DTXSID20198271 |
| FS-9931 |
| (4s)-4-(1-hydroxy-1-methylethyl)-1-cyclohexene-1-carboxylic acid; (-)-oleuropeic acid |
| chembl4796626 , |
| bdbm50553896 |
| AKOS040762985 |
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Cocaine esterase | Homo sapiens (human) | IC50 (µMol) | 1.9000 | 0.0058 | 2.4330 | 6.8000 | AID1697438 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| prostaglandin metabolic process | Cocaine esterase | Homo sapiens (human) |
| xenobiotic metabolic process | Cocaine esterase | Homo sapiens (human) |
| catabolic process | Cocaine esterase | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| methylumbelliferyl-acetate deacetylase activity | Cocaine esterase | Homo sapiens (human) |
| carboxylesterase activity | Cocaine esterase | Homo sapiens (human) |
| carboxylic ester hydrolase activity | Cocaine esterase | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| endoplasmic reticulum | Cocaine esterase | Homo sapiens (human) |
| endoplasmic reticulum lumen | Cocaine esterase | Homo sapiens (human) |
| intracellular membrane-bounded organelle | Cocaine esterase | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1697438 | Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins by fluorescence assay | 2020 | Journal of natural products, 10-23, Volume: 83, Issue:10 | Bioactivity-Guided Discovery of Human Carboxylesterase Inhibitors from the Roots of |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.58) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (11.11%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (88.89%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||