N-homocysteine thiolactonyl retinamide: causes human platelet aggregation [MeSH]
| ID Source | ID |
|---|---|
| PubMed CID | 6505314 |
| SCHEMBL ID | 13672900 |
| MeSH ID | M0150840 |
| Synonym |
|---|
| n-homocysteine thiolactonyl retinamide |
| (2e,4e,6e,8e)-3,7-dimethyl-n-(2-oxothiolan-3-yl)-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenamide |
| nhctr |
| 105918-76-1 |
| retinamide, n-(tetrahydro-2-oxo-3-thienyl)- |
| thioretinamide |
| SCHEMBL13672900 |
| ZFLMWSDRGYCDJF-LYKFAKFTSA-N |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (14.29%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (85.71%) | 84.16% |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| lactic acid | 2-hydroxy monocarboxylic acid | algal metabolite; Daphnia magna metabolite | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 | |
| propylene glycol | glycol; propane-1,2-diols | allergen; human xenobiotic metabolite; mouse metabolite; protic solvent | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 | |
| urethane | carbamate ester | fungal metabolite; mutagen | 1987 | 1989 | 36.0 | low | 0 | 2 | 0 | 0 | 0 | 0 | |
| homocysteine | amino acid zwitterion; homocysteine; serine family amino acid | fundamental metabolite; mouse metabolite | 1987 | 2011 | 30.0 | high | 0 | 3 | 2 | 1 | 1 | 0 | |
| triiodothyronine | tetrahydrothiophenes; thiolactone | human metabolite | 1987 | 2002 | 30.3 | medium | 0 | 1 | 1 | 1 | 0 | 0 | |
| tretinoin | retinoic acid; vitamin A | anti-inflammatory agent; antineoplastic agent; antioxidant; AP-1 antagonist; human metabolite; keratolytic drug; retinoic acid receptor agonist; retinoid X receptor agonist; signalling molecule | 1987 | 2011 | 30.0 | high | 0 | 3 | 2 | 1 | 1 | 0 | |
| cobamamide | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 | |||
| vitamin b 12 | 1989 | 2011 | 27.2 | medium | 0 | 1 | 2 | 1 | 1 | 0 |
| Condition | Indicated | Studies | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Arterial Obstructive Diseases | 0 | 2002 | 2002 | 22.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 | |
| Arterial Occlusive Diseases | 0 | 2002 | 2002 | 22.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 | |
| Arteriosclerosis | 0 | 1990 | 2002 | 28.0 | medium | 0 | 0 | 1 | 1 | 0 | 0 | |
| Cancer of Lung | 0 | 1987 | 1987 | 37.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 | |
| Disease | 0 | 2011 | 2011 | 13.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 | |
| Experimental Neoplasms | 0 | 1989 | 1989 | 35.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 | |
| Lung Neoplasms | 0 | 1987 | 1987 | 37.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 | |
| Rhabdomyosarcoma | 0 | 1987 | 1987 | 37.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 | |
| Weight Gain | 0 | 2002 | 2002 | 22.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 |