| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
aminoglutethimide
Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.. aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position. | 2 | 1 | 0 | dicarboximide;
piperidones;
substituted aniline | adrenergic agent;
anticonvulsant;
antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor |
loliolide
loliolide: RN given refers to (6S-cis)-isomer | 2 | 1 | 0 | benzofurans | metabolite |
aromadedrin
aromadedrin: inhibits protein kinase C; the dihydro makes it a flavone rather than a flavonol. (+)-dihydrokaempferol : A tetrahydroxyflavanone having hydroxy groupa at the 3-, 4'-, 5- and 7-positions. | 2 | 1 | 0 | 4'-hydroxyflavanones;
dihydroflavonols;
secondary alpha-hydroxy ketone;
tetrahydroxyflavanone | metabolite |
moracin c
[no description available] | 2.17 | 1 | 0 | benzofurans | |
moracin m
moracin M: has been isolated from Morus alba L.; structure in first source | 2 | 1 | 0 | benzofurans | |
benzofurans
Benzofurans: Compounds that contain a BENZENE ring fused to a furan ring. | 3.79 | 10 | 0 | | |
marmesin
marmesin: RN given refers to (S)-isomer; nodakenetin is the (R)-isomer | 2 | 1 | 0 | marmesin | |
naringenin
(S)-naringenin : The (S)-enantiomer of naringenin. | 2 | 1 | 0 | (2S)-flavan-4-one;
naringenin | expectorant;
plant metabolite |
resveratrol
trans-resveratrol : A resveratrol in which the double bond has E configuration. | 2.76 | 3 | 0 | resveratrol | antioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger |
stilbenes
Stilbenes: Organic compounds that contain 1,2-diphenylethylene as a functional group.. trans-stilbene : The trans-isomer of stilbene. | 2.85 | 3 | 0 | stilbene | |
isobavachalcone
isobavachalcone: RN given for (E)-isomer; structure in first source. isobavachalcone : A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4' and a prenyl group at position 3'. | 2 | 1 | 0 | chalcones;
polyphenol | antibacterial agent;
metabolite;
platelet aggregation inhibitor |
kuwanon g
kuwanon G: a non-peptide bombesin receptor antagonist; RN refers to (1S-(1alpha,5alpha,6beta))-isomer; structure given in first source. kuwanone G : A tetrahydroxyflavone isolated from the root barks of Morus alba and has been shown to exhibit anti-inflammatory activity. | 3.08 | 4 | 0 | resorcinols;
tetrahydroxyflavone | anti-inflammatory agent;
plant metabolite |
morusin
morusin: from Morus root bark; structure given in first source. morusin : An extended flavonoid that is flavone substituted by hydroxy groups at positions 5, 2' and 4', a prenyl group at position 3 and a 2,2-dimethyl pyran group across positions 7 and 8. | 2.85 | 3 | 0 | extended flavonoid;
trihydroxyflavone | antineoplastic agent;
plant metabolite |
trans-2,3',4,5'-tetrahydroxystilbene
trans-2,3',4,5'-tetrahydroxystilbene: hydroxystilbene oxyresveratrol | 2.1 | 1 | 0 | stilbenoid | |
4-hydroxystilbene
4-hydroxystilbene: RN given refers to cpd without isomeric designation. stilben-4-ol : A phenol having the structure of stilbene with a hydroxy function at C-4 of one of the phenyl rings; the stereochemistry across the alkene bond is not specified. | 2.25 | 1 | 0 | stilben-4-ol | |
broussonin a
broussonin A: has antiviral activity; isolated from Anemarrhena asphodeloides; structure in first source | 2 | 1 | 0 | | |
broussonin b
broussonin B: structure in first source | 2 | 1 | 0 | | |
Isolicoflavonol
[no description available] | 2 | 1 | 0 | flavones | |
2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid
2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid: chromogen in glucose oxidase-peroxidase method for determining serum glucose; used in free radical scavenging assays; structure in first source | 2.1 | 1 | 0 | | |
broussochalcone a
broussochalcone A: RN given for (E)-isomer; inhibits neutrophil respiratory burst; structure in first source | 2 | 1 | 0 | | |
bavachalcone
bavachalcone: structure in first source | 2 | 1 | 0 | chalcones | |
morachalcone a
morachalcone A: tyrosinase inhibitor from the wood of Artocarpus heterophyllus; structure in first source | 2 | 1 | 0 | chalcones | |
2,4,2',4'-Tetrahydroxychalcone
[no description available] | 2 | 1 | 0 | chalcones | |
licoflavone c
licoflavone C: Antimutagenic Agent; a naturally occurring prenyl-flavone extracted from Genista ephedroides; structure in first source | 2.17 | 1 | 0 | | |
bavachin
bavachin: from Psoralea corylifolia (Leguminosae), has osteoblastic proliferation stimulating activity; do not confuse with bavachinin | 2 | 1 | 0 | | |