Compounds > kelampayoside a
Page last updated: 2024-11-12

kelampayoside a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

kelampayoside A: a phenolic apioglucoside from the bark of Anthocephalus chinensis; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
Anthocephalusgenus[no description available]RubiaceaeThe Madder plant family of the order Gentianales (formerly Rubiales), subclass Asteridae, class Magnoliopsida includes important medicinal plants that provide QUININE; IPECAC; and COFFEE. They have opposite leaves and interpetiolar stipules.[MeSH]

Cross-References

ID SourceID
PubMed CID10552637
CHEMBL ID1923077
CHEBI ID68963
MeSH IDM0265425

Synonyms (11)

Synonym
kelampayoside a
chebi:68963 ,
CHEMBL1923077
87562-76-3
3,4,5-trimethoxyphenyl-1-o-beta-d-apiofuranosyl-(1->6)-o-beta-d-glucopyranoside
Q27137315
FS-9123
(2r,3s,4s,5r,6s)-2-[[(2r,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-6-(3,4,5-trimethoxyphenoxy)oxane-3,4,5-triol
3,4,5-trimethoxyphenyl 6-o-d-apio--d-furanosyl--d-glucopyranoside
DTXSID101317142
AKOS040761948
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
metaboliteAny intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
glycosideA glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO-, RS-, RSe-, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID1442887Antiproliferative activity against human MCF7 cells by SRB assay2017Bioorganic & medicinal chemistry letters, 04-15, Volume: 27, Issue:8
Bioactive drimane sesquiterpenoids and aromatic glycosides from Cinnamosma fragrans.
AID632953Cytotoxicity against human CCD-18Co cells after 72 hrs by MTS assay2011Journal of natural products, Nov-28, Volume: 74, Issue:11
Phenolic glycosides from sugar maple (Acer saccharum) bark.
AID1761969Analgesic activity against paclitaxel-induced cold allodynia in C57BL/6 mouse model at 10 mg/kg, po administered at day 14 and day 25 of post paclitaxel stimulation and measured after 1 hr2021Journal of natural products, 03-26, Volume: 84, Issue:3
Aromatic and Aliphatic Apiuronides from the Bark of
AID632952Cytotoxicity against human Caco2 cells after 72 hrs by MTS assay2011Journal of natural products, Nov-28, Volume: 74, Issue:11
Phenolic glycosides from sugar maple (Acer saccharum) bark.
AID632951Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay2011Journal of natural products, Nov-28, Volume: 74, Issue:11
Phenolic glycosides from sugar maple (Acer saccharum) bark.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
oleanolic acid
[no description available]		2.0810hydroxy monocarboxylic acid;
pentacyclic triterpenoid		plant metabolite
camptothecin
NSC 100880: carboxylate (opened lactone) form of camptothecin; RN refers to (S)-isomer; structure given in first source		2.5220delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite
etoposide
[no description available]		2.0610beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor
glucose, (beta-d)-isomer
beta-D-glucose : D-Glucopyranose with beta configuration at the anomeric centre.. (1->4)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->4) linkages.. (1->3)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->3) linkages.		2.7330D-glucopyranoseepitope;
mouse metabolite
polygodial
[no description available]		2.1510aldehyde
scopolin
[no description available]		2.0610beta-D-glucoside;
coumarins;
monosaccharide derivative		plant metabolite
syringaresinol
(+)-syringaresinol : The (7alpha,7'alpha,8alpha,8'alpha)-stereoisomer of syringaresinol.		2.3110syringaresinolantineoplastic agent
acanthoside b
acanthoside B: isolated from the herb Huanghuaren; RN given refers to (1S-(1alpha,3aalpha,4alpha,6aalpha))-isomer		2.0610beta-D-glucosidemetabolite
luteolin
[no description available]		2.08103'-hydroxyflavonoid;
tetrahydroxyflavone		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
c-Jun N-terminal kinase inhibitor;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
immunomodulator;
nephroprotective agent;
plant metabolite;
radical scavenger;
vascular endothelial growth factor receptor antagonist
hydnocarpin
hydnocarpin: structure given in first source; isolated from Hydnocarpus wightiana seeds		2.0810
strictosamide
strictosamide: from Sarcocephalus latifolius; structure in first source		2.0810beta-carbolines
pumiloside
pumiloside: structure in first source		2.0810glycoside
3,5-dimethoxy-4-hydroxybenzyl alcohol-4-O-beta-D-glucopyranoside
3,5-dimethoxy-4-hydroxybenzyl alcohol-4-O-beta-D-glucopyranoside : A monosaccharide derivative that consists of 4-(hydroxymethyl)-2,6-dimethoxyphenol attached to a beta-D-glucopyranosyl residue at position 1 via a glycosidic linkage. Isolated from Acacia mearnsii it exhibits cytotoxic activity.		2.0610aromatic ether;
benzyl alcohols;
beta-D-glucoside;
monosaccharide derivative;
primary alcohol		antineoplastic agent;
metabolite
cinnamosmolide
cinnamosmolide: isolated from several species of Canellaceae family; structure in first source		2.1510
helicide
helicide: structure given in first source		2.1510glycoside
Icariside E4
icariside E4: has antinociceptive activity; isolated from Tabebuia roseo-alba; structure in first source		2.0610benzofuransmetabolite
vanilloloside
[no description available]		2.0610glycosidemetabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Breast Cancer
[description not available]		02.1510
Breast Neoplasms
Tumors or cancer of the human BREAST.		02.1510
Nerve Pain
[description not available]		02.3110
Neuralgia
Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.		02.3110