fc 80 profile

perfluorobutyl tetrahydrofuran: was MH 1975-92 (see under FLUOROCARBONS 1978-90, see under FURANS 1975-77); FC-80 & PERFLUOROCHEMICAL FC-80 were see PERFLUOROBUTYL TETRAHYDROFURAN 1978-92; use FLUOROCARBONS to search PERFLUOROBUTYL TETRAHYDROFURAN 1978-92 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	134921
CHEBI ID	39029
SCHEMBL ID	104183
MeSH ID	M0197600

Synonym
furan, tetrahydro(nonafluorobutyl)-
fx-80
(perfluorobutyl)tetrahydrofuran
perfluorobutyl tetrahydrofuran
perfluorochemical fc-80
fc-80
26446-59-3
2-(nonafluorobutyl)tetrahydrofuran
CHEBI:39029
fx 80
2-perfluorobutyltetrahydrofuran
perfluorobutyltetrahydrofuran
2-(1,1,2,2,3,3,4,4,4-nonafluorobutyl)oxolane
25962-44-1
SCHEMBL104183
DTXSID90276353
(nonafluorobutyl)tetra hydrofuran
Q27118100
cjfuepjvifjoou-uhfffaoysa-n
tetrahydro(perfluorobutyl)furan

Excerpt	Relevance	Reference
" Although PFC evaporation from the lungs is in part dependent on ventilation strategy and positioning, guidelines for initial and replacement dosing are unclear."	( Perfluorochemical elimination from the lungs: effect of initial dose. Fox, WW; Philips, CM; Shaffer, TH; Weis, CM; Wolfson, MR, 2000)	0.31

Class	Description
organofluorine compound	An organofluorine compound is a compound containing at least one carbon-fluorine bond.
alkyltetrahydrofuran
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	5 (45.45)	18.2507
2000's	5 (45.45)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (9.09)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	1 (8.33%)	5.53%
Reviews	1 (8.33%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	10 (83.33%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
urea pseudourea: clinical use; structure. isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.	3.8	1	1	isourea; monocarboxylic acid amide; one-carbon compound	Daphnia magna metabolite; Escherichia coli metabolite; fertilizer; flour treatment agent; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
adenosine quinquefolan B: isolated from roots of Panax quinquefolium L.; RN not in Chemline 10/87; RN from Toxlit	2.67	3	0	adenosines; purines D-ribonucleoside	analgesic; anti-arrhythmia drug; fundamental metabolite; human metabolite; vasodilator agent
fc 75 [no description available]	2	1	0	alkyltetrahydrofuran; organofluorine compound
cellulose triacetate cellulose triacetate: for hemodialysis filtration	3.8	1	1
raffinose Raffinose: A trisaccharide occurring in Australian manna (from Eucalyptus spp, Myrtaceae) and in cottonseed meal.. raffinose : A trisaccharide composed of alpha-D-galactopyranose, alpha-D-glucopyranose and beta-D-fructofuranose joined in sequence by 1->6 and 1<->2 glycosidic linkages, respectively.	2.67	3	0	raffinose family oligosaccharide; trisaccharide	mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
cellulose DEAE-Cellulose: Cellulose derivative used in chromatography, as ion-exchange material, and for various industrial applications.	3.8	1	1	glycoside
allopurinol Allopurinol: A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.. allopurinol : A bicyclic structure comprising a pyrazole ring fused to a hydroxy-substituted pyrimidine ring.	2.67	3	0	nucleobase analogue; organic heterobicyclic compound	antimetabolite; EC 1.17.3.2 (xanthine oxidase) inhibitor; gout suppressant; radical scavenger

Condition	Relationship Strength	Studies	Trials
Innate Inflammatory Response [description not available]	3.8	1	1
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.	3.8	1	1
Benign Neoplasms [description not available]	2.93	1	0
Cardiovascular Diseases Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.	2.93	1	0
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	2.93	1	0
Anoxemia [description not available]	2.03	1	0
MODS [description not available]	2.03	1	0
Injury, Ischemia-Reperfusion [description not available]	2.03	1	0
Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms.	2.03	1	0
Multiple Organ Failure A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.	2.03	1	0
Reperfusion Injury Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.	2.03	1	0
Ischemia A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.	1.98	1	0
Experimental Lung Inflammation Inflammation of any part, segment or lobe, of the lung parenchyma.	2	1	0
Pneumonia Infection of the lung often accompanied by inflammation.	2	1	0
Chronic Lung Injury [description not available]	2	1	0

fc 80

Description

Cross-References

Synonyms (20)

Research Excerpts

Dosage Studied

Drug Classes (2)

Research

Studies (11)

Market Indicators

Research Demand Index: 35.65

Study Types