Pathways > Base-Excision Repair, AP Site Formation
Page last updated: 2024-10-06
Base-Excision Repair, AP Site Formation
Proteins (15)
| Protein | Synonyms | Taxonomy |
|---|
| Endonuclease III-like protein 1 | hNTH1; EC 3.2.2.-; EC 4.2.99.18; Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase; DNA glycosylase/AP lyase | Homo sapiens (human) |
| Protection of telomeres protein 1 | hPot1; POT1-like telomere end-binding protein | Homo sapiens (human) |
| Endonuclease 8-like 1 | EC 3.2.2.-; EC 4.2.99.18; DNA glycosylase/AP lyase Neil1; DNA-(apurinic or apyrimidinic site) lyase Neil1; Endonuclease VIII-like 1; FPG1; Nei homolog 1; NEH1; Nei-like protein 1 | Homo sapiens (human) |
| Histone H4 | | Homo sapiens (human) |
| N-glycosylase/DNA lyase | | Homo sapiens (human) |
| DNA-3-methyladenine glycosylase | EC 3.2.2.21; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; ADPG; N-methylpurine-DNA glycosylase | Homo sapiens (human) |
| Telomeric repeat-binding factor 2-interacting protein 1 | TERF2-interacting telomeric protein 1; TRF2-interacting telomeric protein 1; Dopamine receptor-interacting protein 5; Repressor/activator protein 1 homolog; RAP1 homolog; hRap1 | Homo sapiens (human) |
| Endonuclease 8-like 3 | EC 3.2.2.-; EC 4.2.99.18; DNA glycosylase FPG2; DNA glycosylase/AP lyase Neil3; Endonuclease VIII-like 3; Nei-like protein 3 | Homo sapiens (human) |
| Endonuclease 8-like 2 | EC 3.2.2.-; EC 4.2.99.18; DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; Endonuclease VIII-like 2; Nei homolog 2; NEH2; Nei-like protein 2 | Homo sapiens (human) |
| Methyl-CpG-binding domain protein 4 | EC 3.2.2.-; Methyl-CpG-binding endonuclease 1; Methyl-CpG-binding protein MBD4; Mismatch-specific DNA N-glycosylase | Homo sapiens (human) |
| G/T mismatch-specific thymine DNA glycosylase | EC 3.2.2.29; Thymine-DNA glycosylase; hTDG | Homo sapiens (human) |
| Histone H3.1t | H3/t; H3t; H3/g; Histone H3.4 | Homo sapiens (human) |
| Single-strand selective monofunctional uracil DNA glycosylase | EC 3.2.2.- | Homo sapiens (human) |
| Adrenocortical dysplasia protein homolog | POT1 and TIN2-interacting protein | Homo sapiens (human) |
| TERF1-interacting nuclear factor 2 | TRF1-interacting nuclear protein 2 | Homo sapiens (human) |
Compounds (16)
| Compound | Description |
|---|
| adenine | A purine base and a fundamental unit of ADENINE NUCLEOTIDES. |
| 3-methyladenine | an inflammation mediator and autophagy inhibitor |
| 8-oxyguanine | structure given in first source |
| spiroiminodihydantoin | structure in first source |
| hypoxanthine | A purine and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the salvage pathway. |
| 3,n(4)-ethanocytosine | |
| 1,n(6)-ethenoadenine | biologically active fluorescent derivatives of this cpd potentially valuable in studies concerning interactions between adenine cpds & various enzymes for which they serve as substrates or co-factors; structure |
| thymine | One of four constituent bases of DNA. |
| 4,6-diamino-5-n-formamidopyrimidine | formed when adenine is exposed to ionizing radiation |
| uracil | One of four nucleotide bases in the nucleic acid RNA. |
| 2,6-diamino-4-hydroxy-5-formamidopyrimidine | structure given in first source |
| cytosine glycol | structure given in first source |
| thymine glycol | forms photodimers (thymine dimers) under UV; RN given refers to cpd without isomeric designation |
| dihydrouracil | |
| guanidinohydantoin | structure in first source |
| 5-hydroxyuracil | used in treatment of colonic adenocarcinoma |