Page last updated: 2024-10-06

Base-Excision Repair, AP Site Formation

Proteins (15)

ProteinSynonymsTaxonomy
Endonuclease III-like protein 1hNTH1; EC 3.2.2.-; EC 4.2.99.18; Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase; DNA glycosylase/AP lyaseHomo sapiens (human)
Protection of telomeres protein 1hPot1; POT1-like telomere end-binding proteinHomo sapiens (human)
Endonuclease 8-like 1EC 3.2.2.-; EC 4.2.99.18; DNA glycosylase/AP lyase Neil1; DNA-(apurinic or apyrimidinic site) lyase Neil1; Endonuclease VIII-like 1; FPG1; Nei homolog 1; NEH1; Nei-like protein 1Homo sapiens (human)
Histone H4Homo sapiens (human)
N-glycosylase/DNA lyaseHomo sapiens (human)
DNA-3-methyladenine glycosylaseEC 3.2.2.21; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; ADPG; N-methylpurine-DNA glycosylaseHomo sapiens (human)
Telomeric repeat-binding factor 2-interacting protein 1TERF2-interacting telomeric protein 1; TRF2-interacting telomeric protein 1; Dopamine receptor-interacting protein 5; Repressor/activator protein 1 homolog; RAP1 homolog; hRap1Homo sapiens (human)
Endonuclease 8-like 3EC 3.2.2.-; EC 4.2.99.18; DNA glycosylase FPG2; DNA glycosylase/AP lyase Neil3; Endonuclease VIII-like 3; Nei-like protein 3Homo sapiens (human)
Endonuclease 8-like 2EC 3.2.2.-; EC 4.2.99.18; DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; Endonuclease VIII-like 2; Nei homolog 2; NEH2; Nei-like protein 2Homo sapiens (human)
Methyl-CpG-binding domain protein 4EC 3.2.2.-; Methyl-CpG-binding endonuclease 1; Methyl-CpG-binding protein MBD4; Mismatch-specific DNA N-glycosylaseHomo sapiens (human)
G/T mismatch-specific thymine DNA glycosylaseEC 3.2.2.29; Thymine-DNA glycosylase; hTDGHomo sapiens (human)
Histone H3.1tH3/t; H3t; H3/g; Histone H3.4Homo sapiens (human)
Single-strand selective monofunctional uracil DNA glycosylaseEC 3.2.2.-Homo sapiens (human)
Adrenocortical dysplasia protein homologPOT1 and TIN2-interacting proteinHomo sapiens (human)
TERF1-interacting nuclear factor 2TRF1-interacting nuclear protein 2Homo sapiens (human)

Compounds (16)

CompoundDescription
adenineA purine base and a fundamental unit of ADENINE NUCLEOTIDES.
3-methyladeninean inflammation mediator and autophagy inhibitor
8-oxyguaninestructure given in first source
spiroiminodihydantoinstructure in first source
hypoxanthineA purine and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the salvage pathway.
3,n(4)-ethanocytosine
1,n(6)-ethenoadeninebiologically active fluorescent derivatives of this cpd potentially valuable in studies concerning interactions between adenine cpds & various enzymes for which they serve as substrates or co-factors; structure
thymineOne of four constituent bases of DNA.
4,6-diamino-5-n-formamidopyrimidineformed when adenine is exposed to ionizing radiation
uracilOne of four nucleotide bases in the nucleic acid RNA.
2,6-diamino-4-hydroxy-5-formamidopyrimidinestructure given in first source
cytosine glycolstructure given in first source
thymine glycolforms photodimers (thymine dimers) under UV; RN given refers to cpd without isomeric designation
dihydrouracil
guanidinohydantoinstructure in first source
5-hydroxyuracilused in treatment of colonic adenocarcinoma