Page last updated: 2024-12-07
2-hydroxycarbazole
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
2-hydroxycarbazole: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 93551 |
| CHEMBL ID | 1170901 |
| SCHEMBL ID | 150279 |
| MeSH ID | M0183047 |
Synonyms (33)
| Synonym |
|---|
| OPREA1_146166 |
| 2-hydroxycarbazole |
| ccris 5301 |
| brn 0135859 |
| carbazol-2-ol |
| einecs 201-699-7 |
| 2-hydroxycarbazole, 97% |
| 9h-carbazol-2-ol |
| AKOS001079611 |
| gwpgdzpxozatkl-uhfffaoysa- |
| inchi=1/c12h9no/c14-8-5-6-10-9-3-1-2-4-11(9)13-12(10)7-8/h1-7,13-14h |
| HMS1719L15 |
| CHEMBL1170901 |
| 86-79-3 |
| A841830 |
| 5-21-04-00005 (beilstein handbook reference) |
| FT-0602043 |
| SCHEMBL150279 |
| DTXSID50235340 |
| 2-hydroxy-9h-carbazole |
| 2-hydroxy-9h-carbazol |
| mfcd00004962 |
| CS-0046240 |
| 2-carbazolol |
| STL554147 |
| F16106 |
| SH4E4EQ2YZ |
| AS-15921 |
| OL10010 |
| AMY8709 |
| SY047619 |
| EN300-16648 |
| Z56347314 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (4)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3 | High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID491360 | Cytotoxicity against human HeLa cells at 60 uM after 48 hrs by MTT assay | 2010 | Journal of medicinal chemistry, Jul-08, Volume: 53, Issue:13 | Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds. |
| AID491351 | Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity at 20 uM after 30 mins by luciferase-derived luminescence assay | 2010 | Journal of medicinal chemistry, Jul-08, Volume: 53, Issue:13 | Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (9)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 19.84
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (19.84) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||