Assay ID | Title | Year | Journal | Article |
AID127431 | Inhibition of Mitogen-activated protein kinase p38 beta at 1 uM | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID660757 | Inhibition of p38alpha kinase | 2011 | ACS medicinal chemistry letters, Oct-13, Volume: 2, Issue:10
| The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor. |
AID127255 | Inhibitory concentration against mitogen-activated protein kinase p38 alpha | 2001 | Bioorganic & medicinal chemistry letters, May-07, Volume: 11, Issue:9
| Phenoxypyrimidine inhibitors of p38alpha kinase: synthesis and statistical evaluation of the p38 inhibitory potencies of a series of 1-(piperidin-4-yl)-4-(4-fluorophenyl)-5-(2-phenoxypyrimidin-4-yl) imidazoles. |
AID127257 | Inhibition of Mitogen-activated protein kinase p38 alpha at 1 uM | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID126938 | Inhibition of Mitogen-activated protein kinase 3/Mitogen-activated protein kinase 1 (ERK) at 10 uM | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID126946 | In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alpha | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID303075 | Inhibition of p38 MAPK activity assessed as EGFR phosphorylation | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Synthesis, crystal structure, and activity of pyrazole-based inhibitors of p38 kinase. |
AID160348 | In vitro inhibition of cytokine IL-2 release by human polymorphonuclear cells | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID219337 | Inhibition of c-Jun N-terminal kinase 1 at 10 uM | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID160349 | In vitro inhibition of cytokine IL-6 release by human polymorphonuclear cells | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID160350 | In vitro inhibition of cytokine IL-8 release by human polymorphonuclear cells | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID160351 | In vitro inhibition of gamma-interferon release by human polymorphonuclear cells | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID160346 | In vitro inhibition of cytokine IL-10 release by human polymorphonuclear cells | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID160344 | In vitro inhibition of IL1-beta release from LPS stimulated human peripheral blood mononuclear cells. | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID127433 | Inhibition of Mitogen-activated protein kinase p38 gamma at 1 uM | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID160347 | In vitro inhibition of cytokine IL-12 release by human polymorphonuclear cells | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID127432 | Inhibition of Mitogen-activated protein kinase p38 delta at 1 uM | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID160345 | In vitro inhibition of TNF-alpha release from LPS stimulated human peripheral blood mononuclear cells. | 2003 | Journal of medicinal chemistry, Dec-18, Volume: 46, Issue:26
| Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity. |
AID1799438 | Activation Assay from Article 10.1016/s1074-5521(97)90194-0: \\The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase.\\ | 1997 | Chemistry & biology, Jun, Volume: 4, Issue:6
| The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |