Page last updated: 2024-12-05
thiomuscimol
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
thiomuscimol: used as GABA analog; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 5448 |
| CHEMBL ID | 133628 |
| SCHEMBL ID | 7778711 |
| MeSH ID | M0074282 |
Synonyms (20)
| Synonym |
|---|
| thiomuscimol |
| CHEMBL133628 |
| 5-(aminomethyl)isothiazol-3(2h)-one |
| 5-(aminomethyl)-3(2h)-isothiazolone |
| 5-(aminomethyl)-1,2-thiazol-3-one |
| 62020-54-6 |
| 5-aminomethyl-3-isothiazolol |
| 5-(aminomethyl)- 3(2h)-isothiazolone |
| nsc_5448 |
| bdbm85196 |
| cas_5448 |
| AKOS006338836 |
| FT-0675183 |
| SCHEMBL7778711 |
| DTXSID00211078 |
| AKOS030538857 |
| thiomuscimol hydrobromide |
| Q15634088 |
| 5-(aminomethyl)-2,3-dihydro-1,2-thiazol-3-one |
| EN300-7298563 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (1)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID72155 | Binding affinity in vivo for gamma-aminobutyric-acid A receptor measured by its ability to displace [3H]-GABA agonist from rat brain preparations after iv injection. | 1992 | Journal of medicinal chemistry, Oct-30, Volume: 35, Issue:22 | Condensation of muscimol or thiomuscimol with aminopyridazines yields GABA-A antagonists. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 23.06
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (23.06) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||