thiomuscimol has been researched along with Amyotrophic Lateral Sclerosis in 1 studies
thiomuscimol: used as GABA analog; structure
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jaronen, M | 1 |
| Vehviläinen, P | 1 |
| Malm, T | 1 |
| Keksa-Goldsteine, V | 1 |
| Pollari, E | 1 |
| Valonen, P | 1 |
| Koistinaho, J | 1 |
| Goldsteins, G | 1 |
1 other study available for thiomuscimol and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Protein disulfide isomerase in ALS mouse glia links protein misfolding with NADPH oxidase-catalyzed superoxide production.
Topics: Amyotrophic Lateral Sclerosis; Animals; Anterior Horn Cells; Astrocytes; Cell Line; Enzyme Activatio | 2013 |