Compounds > tert-butyl acrylate
Page last updated: 2024-11-05

tert-butyl acrylate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

tert-Butyl acrylate (tBA) is a colorless liquid monomer that is widely used in the production of polymers, such as poly(tert-butyl acrylate) (PtBA). It is synthesized by the reaction of tert-butanol with acrylic acid in the presence of an acid catalyst. tBA is a versatile monomer that can be polymerized by various methods, including free radical polymerization, anionic polymerization, and atom transfer radical polymerization. The resulting polymers exhibit a range of properties, including good flexibility, low glass transition temperature, and excellent adhesion. PtBA is used in a variety of applications, including adhesives, coatings, sealants, and elastomers. tBA is also used as a starting material for the synthesis of other monomers and polymers. The importance of tBA lies in its ability to impart unique properties to polymers, such as flexibility and low glass transition temperature, which are valuable in a wide range of applications. It is studied extensively due to its versatility, reactivity, and the potential for creating novel polymers with desirable properties. tBA is also of interest in the development of biodegradable and biocompatible polymers for biomedical applications.'

tert-butyl acrylate: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID15458
CHEMBL ID3560064
SCHEMBL ID30658
MeSH IDM0513016

Synonyms (63)

Synonym
LS-13315
acrylic acid, tert-butyl ester
2-propenoic acid, 1,1-dimethylethyl ester
tert-butyl acrylate
1663-39-4
nsc20950
nsc-20950
2-propenoic acid,1-dimethylethyl ester
tert-butyl acrylate, contains 10-20 ppm monomethyl ether hydroquinone as inhibitor, 98%
einecs 216-768-7
hsdb 5452
nsc 20950
ccris 7035
tert-butyl propenoate
acrylic acid tert-butyl ester
tert-butyl prop-2-enoate
isxscdlogdjunj-uhfffaoysa-
inchi=1/c7h12o2/c1-5-6(8)9-7(2,3)4/h5h,1h2,2-4h3
A810720
2-propenoic acid tert-butyl ester
NCGC00248926-01
AKOS009157040
tert-butylacrylate
ec 216-768-7
unii-92m2cd1o3g
92m2cd1o3g ,
tox21_201117
dtxcid409652
dtxsid8029652 ,
NCGC00258669-01
cas-1663-39-4
FT-0633742
BP-21063
SCHEMBL30658
tert-butyl 2-propenoate
1,1-dimethylethyl 2-propenoate
butyl acrylate, tert-
2-propenoic acid, 1,1-dimethylethyl ester [hsdb]
acrylic acid tert.-butyl ester
tert-butyl-prop-2-enoate
t-butyl acrylate
t-buty acrylate
t-butylacrylate
2-propenoic acid t-butyl ester
ter-butyl-acrylate
tert-butyl-acrylate
acrylic tert-butyl ester
tert.-butyl acrylate
tert. butyl acrylate
acrylic acid-tert-butyl ester
tert butyl acrylate
acrylic acid t-butyl ester
CHEMBL3560064
mfcd00008809
F0001-0604
tert-butyl acrylate, (stabilized with mehq)
tert-butyl acrylate (stabilized with mehq)
J-010272
tert-butyl acrylate contains 10-100 ppm monomethyl ether hydroquinone as inhibitor
acrylics
Q25385680
EN300-39268
STL185696
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (1)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency33.12160.003041.611522,387.1992AID1159552
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (24)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (20.83)29.6817
2010's19 (79.17)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 51.47

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index51.47 (24.57)
Research Supply Index3.22 (2.92)
Research Growth Index4.92 (4.65)
Search Engine Demand Index76.90 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (51.47)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other24 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
benzaldehyde
[no description available]		2.0610benzaldehydesEC 3.1.1.3 (triacylglycerol lipase) inhibitor;
EC 3.5.5.1 (nitrilase) inhibitor;
flavouring agent;
fragrance;
odorant receptor agonist;
plant metabolite
benzene
[no description available]		2.2110aromatic annulene;
benzenes;
volatile organic compound		carcinogenic agent;
environmental contaminant;
non-polar solvent
bromide
Bromides: Salts of hydrobromic acid, HBr, with the bromine atom in the 1- oxidation state. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)		2.0510halide anion;
monoatomic bromine
methane
Methane: The simplest saturated hydrocarbon. It is a colorless, flammable gas, slightly soluble in water. It is one of the chief constituents of natural gas and is formed in the decomposition of organic matter. (Grant & Hackh's Chemical Dictionary, 5th ed). methane : A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. -161degreeC).		2.0510alkane;
gas molecular entity;
mononuclear parent hydride;
one-carbon compound		bacterial metabolite;
fossil fuel;
greenhouse gas
iodine
Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.. diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..		2.2110diatomic iodinenutrient
nitroxyl
nitroxyl: hydroxamic acid oxidized to nitroxyl free radical. nitroxyl : A nitrogen oxoacid consisting of an oxygen atom double-bonded to an NH group.		2.0410nitrogen oxoacid
pyrazole
1H-pyrazole : The 1H-tautomer of pyrazole.		2.1110pyrazole
acrylic acid
acrylic acid: RN given refers to parent cpd. acrylic acid : A alpha,beta-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group.		3.8100alpha,beta-unsaturated monocarboxylic acidmetabolite
methylmethacrylate
Methylmethacrylate: The methyl ester of methacrylic acid. It polymerizes easily to form POLYMETHYL METHACRYLATE. It is used as a bone cement.. methyl methacrylate : An enoate ester having methacrylic acid as the carboxylic acid component and methanol as the alcohol component.		2.0710enoate ester;
methyl ester		allergen;
polymerisation monomer
carbazole
carbazole: structure in first source		2.0610carbazole
methyl acrylate
[no description available]		2.110enoate ester
styrene
Styrene: A colorless, toxic liquid with a strong aromatic odor. It is used to make rubbers, polymers and copolymers, and polystyrene plastics.. styrene : A vinylarene that is benzene carrying a vinyl group. It has been isolated from the benzoin resin produced by Styrax species.		2.9740styrenes;
vinylarene;
volatile organic compound		mouse metabolite;
mutagen;
plant metabolite
n-benzyl-n,n-dimethylamine
[no description available]		2.0510
glycidyl methacrylate
glycidyl methacrylate: RN given refers to monomer. glycidyl methacrylate : An enoate ester obtained by formal condensation of the carboxy group of methacrylic acid with the hydroxy group of glycidol.		2.0610enoate ester;
epoxide
3-hydroxybutanal
[no description available]		2.0610
tetrahydrofuran
oxolane : A cyclic ether that is butane in which one hydrogen from each methyl group is substituted by an oxygen.		2.0610cyclic ether;
oxolanes;
saturated organic heteromonocyclic parent;
volatile organic compound		polar aprotic solvent
ethyl acrylate
[no description available]		2.0610enoate ester
n-butyl acrylate
butyl acrylate : An acrylate ester obtained by the formal condensation of the hydroxy group of butan-1-ol with the carboxy group of acrylic acid.		2.1510acrylate ester
2-bromopropionic acid, (dl)-isomer
2-bromopropionic acid: RN given refers to cpd without isomeric designation		2.0610
n-isopropylacrylamide
N-isopropylacrylamide: can polymerize with glycidyl acrylate to form reactive water-soluble polymer that can react with the amino groups of enzymes-proteins or other ligands		2.1510
2-(dimethylamino)ethyl methacrylate
2-(dimethylamino)ethyl methacrylate: reducing agent; structure given in first source		2.0610
palladium
Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46.		2.7630metal allergen;
nickel group element atom;
platinum group metal atom
rhodium
Rhodium: A hard and rare metal of the platinum group, atomic number 45, atomic weight 102.905, symbol Rh.. rhodium atom : A cobalt group element atom of atomic number 45.		2.4920cobalt group element atom
palladium chloride
palladium chloride: RN given refers to parent cpd; structure. palladium(II) chloride : A palladium coordination entity consisting of palladium(II) bound to two chlorine atoms.		2.0510palladium coordination entitycatalyst
phosphine
phosphane : The simplest phosphine, consisting of a single phosphorus atom with three hydrogens attached.. phosphine : Phosphane (PH3) and compounds derived from it by substituting one, two or three hydrogen atoms by hydrocarbyl groups: RPH2, R2PH, R3P (R =/= H) are called primary, secondary and tertiary phosphines, respectively. A specific phosphine is preferably named as a substituted phosphane.		2.0510mononuclear parent hydride;
phosphanes;
phosphine		carcinogenic agent;
fumigant insecticide
alkenes
[no description available]		2.110
paclitaxel
Taxus: Genus of coniferous yew trees or shrubs, several species of which have medicinal uses. Notable is the Pacific yew, Taxus brevifolia, which is used to make the anti-neoplastic drug taxol (PACLITAXEL).		2.0710taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
carbene
carbene: electrically neutral species H2C: and its derivatives, in which the carbon is covalently bonded to two univalent groups of any kind or a divalent group and bears two nonbonding electrons; carbene is the name of the parent hydride :CH2 ; hence, the name dichlorocarbene for :CCl2. However, names for acyclic and cyclic hydrocarbons containing one or more divalent carbon atoms are derived from the name of the corresponding all-4-hydrocarbon using the suffix -ylidene; methylene carbene also available. carbene : The electrically neutral species H2C(2.) and its derivatives, in which the carbon is covalently bonded to two univalent groups of any kind or a divalent group and bears two nonbonding electrons, which may be spin-paired (singlet state) or spin-non-paired (triplet state).		2.0510carbene;
methanediyl
tert-butyl cinnamate
tert-butyl cinnamate: structure in first source		2.0510
ConditionIndicatedRelationship StrengthStudiesTrials