Page last updated: 2024-12-08
succinimidyl carbonate
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
succinimidyl carbonate: activates polyethylene glycol which is coupled to proteins; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 148208 |
| SCHEMBL ID | 57128 |
| MeSH ID | M0227587 |
Synonyms (10)
| Synonym |
|---|
| succinimidyl carbonate |
| (2,5-dioxopyrrolidin-1-yl) hydrogen carbonate |
| 2,5-pyrrolidinedione, 1-(carboxyoxy)- |
| 135680-78-3 |
| 1-(carboxyoxy)-2,5-pyrrolidinedione |
| 2,5-pyrrolidinedione,1-(carboxyoxy)- |
| SCHEMBL57128 |
| DTXSID50159491 |
| n-(carboxyoxy)succinimide |
| (2,5-dioxopyrrolidin-1-yl)oxyformic acid |
Research Excerpts
Dosage Studied
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using slow-cleaving linkers, the latter may provide a generic format for once-a-month dosage forms of potent drugs." | ( Predictable and tunable half-life extension of therapeutic agents by controlled chemical release from macromolecular conjugates. Ashley, GW; Reid, R; Robinson, L; Santi, DV; Schneider, EL, 2012) | 0.38 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (14)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 11 (78.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 27.81
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (27.81) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (6.25%) | 6.00% |
| Case Studies | 1 (6.25%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 14 (87.50%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||