Page last updated: 2024-12-10

stypoldione

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

stypoldione: ortho-quinone from brown algae Stypopodium zonale; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID3034636
MeSH IDM0118819

Synonyms (12)

Synonym
stypoldione
nsc339672 ,
71103-05-4
(1s,2s,4ar,4bs,7s,8ar,10ar)-7-hydroxy-2,4b,7',8,8,10a-hexamethyl-spiro[2,3,4,4a,5,6,7,8a,9,10-decahydrophenanthrene-1,2'-3h-benzofuran]-4',5'-dione
spiro[benzofuran-2(3h),1'(2'h)-phenanthrene]-4,5-dione, 3',4',4'a,4'b,5',6',7',8',8'a,9',10',10'a-dodecahydro-7'-hydroxy-2',4'b,7,8',8',10'a-hexamethyl-, (2s,2's,4b's,7's,10a'r)-
(1s,2s,4ar,4bs,7s,8ar,10ar)-7-hydroxy-2,4b,7',8,8,10a-hexamethylspiro[2,3,4,4a,5,6,7,8a,9,10-decahydrophenanthrene-1,2'-3h-1-benzofuran]-4',5'-dione
16,24-cyclo-13,17-secochola-16,20(22)-diene-23,24-dione, 14,17-epoxy-3-hydroxy-4,4,8-trimethyl-, (3beta,5alpha,13alpha)-
y7jz2j63q7 ,
unii-y7jz2j63q7
nsc 339672
XS177357
spiro[benzofuran-2(3h),1'(2'h)-phenanthrene]-4,5-dione, 3',4',4'a,4'b,5',6',7',8',8'a,9',10',10'a-dodecahydro-7'-hydroxy-2',4'b,7,8',8',10'a-hexamethyl-, (1's,2's,4'ar,4'bs,7's,8'ar,10'ar)-

Research Excerpts

Overview

Stypoldione is a marine natural product that inhibits cells division in marine embryos and in mammalian cell cultures.

ExcerptReferenceRelevance
"Stypoldione is a marine natural product that inhibits cells division in marine embryos and in mammalian cell cultures. "( Selective inhibition of cytokinesis in sea urchin embryos by low concentrations of stypoldione, a marine natural product that reacts with sulfhydryl groups.
Asai, DJ; Jacobs, RS; O'Brien, ET; Wilson, L, 1989
)
1.94
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (50.00)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (12.50%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (87.50%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]